FDTOa_FAF Pharmaceutical Toxicology

Faculty of Pharmacy
Autumn 2025
Extent and Intensity
2/0/0. 5 credit(s). Type of Completion: zk (examination).
In-person direct teaching
Teacher(s)
doc. MVDr. Pavel Suchý, Ph.D. (lecturer)
Guaranteed by
doc. MVDr. Pavel Suchý, Ph.D.
Faculty of Pharmacy
Supplier department: Department of Pharmacology and Toxicology – Departments – Faculty of Pharmacy
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
A follow-up of the Master's degree programme deepens students' knowledge of pharmaceutical toxicology and research in the area of evaluation of toxicity of new biologically active substances and undesired drug effects.

Learning outcomes
Advanced knowledge of toxicology focusing on pharmaceutical toxicology, verification of safety of new and potentially effective substances, clinical evaluation of drugs and assessment of their possible side effects.
Syllabus
Students will obtain theoretical and practical knowledge of toxicological methods used in testing of biologically active substances (potential drugs), on in silico, in vitro and in vivo studies. They will learn about clinical evaluation of new pharmaceutical drugs (especially the first and second phase of clinical evaluation), and about methods monitoring their use in clinical practice, recognize and assess undesired effects and analyze the risk-benefit ratio associated with their use.
Literature
    recommended literature
  • LINHART, Igor. Toxikologie : interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. 3. upravené a rozšířené. Praha: Vysoká škola chemicko-technologická v Praze, 2022, 411 stran. ISBN 9788075921031. info
  • Balíková, M. Forenzní a klinická toxikologie. Galén Praha, 2017. ISBN 9788074923043. info
  • Will, Y. Drug discovery toxicology. New Jersey, 2016. info
  • LEGATH, J., SUCHÝ, P. aj. TOXIKOLOGIA - kompendium pro farmaceuty. Košice, 2016. ISBN 978-80-8077-521-6. info
  • Handbook of toxicology. Edited by Michael J. Derelanko - Carol Auletta. Third edition. Boca Raton: CRC Press, 2014, lii, 968. ISBN 9781439890134. info
  • CASARETT DOULL¨S. Essentials of Toxicology. 2010. ISBN 0071742743. info
Teaching methods
discussion, group projects, homework
Assessment methods
oral examination
Language of instruction
English
The course is also listed under the following terms Spring 2025, Spring 2026.
  • Enrolment Statistics (Autumn 2025, recent)
  • Permalink: https://is.muni.cz/course/pharm/autumn2025/FDTOa_FAF