PřF:Bi0311 Clinical Haematology - Course Information
Bi0311 Clinical Haematology
Faculty of ScienceAutumn 2024
- Extent and Intensity
- 2/0/0. 2 credit(s) (příf plus uk k 1 zk 2 plus 1 > 4). Type of Completion: zk (examination).
- Teacher(s)
- RNDr. Ludmila Bourková (lecturer)
MUDr. Alena Buliková, Ph.D. (lecturer)
Mgr. Zbyněk Čech (lecturer)
MUDr. Jan Kamelander (lecturer)
MUDr. Jarmila Kissová, Ph.D. (lecturer)
prof. MUDr. Miroslav Penka, CSc. (lecturer)
MUDr. Pavel Polák, Ph.D. (lecturer)
MUDr. Gabriela Romanová, Ph.D. (lecturer)
Mgr. Lucie Říhová, Ph.D. (lecturer)
MUDr. Petr Smejkal, Ph.D. (lecturer)
RNDr. Jiřina Zavřelová (lecturer) - Guaranteed by
- prof. MUDr. Miroslav Penka, CSc.
Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine
Contact Person: RNDr. Ludmila Bourková
Supplier department: Department of Laboratory Methods – Departments of Non-medical Branches – Faculty of Medicine - Timetable
- Mon 16:00–17:50 A20/207
- Course Enrolment Limitations
- The course is only offered to the students of the study fields the course is directly associated with.
- fields of study / plans the course is directly associated with
- Medical Genetics and Molecular Diagnostics (programme PřF, B-BI)
- Medical Genetics and Molecular Diagnostics (programme PřF, B-LGM)
- Course objectives
- This course includes information about the origin, development, structure and function of the system of hematopoietic cells and organs as well as of the blood clotting system. Both of them are described not only in health but also during various diseases inherited and acquired. Students will receive information summarizing pathophysiologic mechanisms, clinical and mainly laboratory findings in hematologic diseases and laboratory assays serving for treatment’s maintenance. The knowledge will allow students to interpret results obtained during hematological laboratory examination for diagnosis establishing and/or for differential diagnoses.
- Learning outcomes
- Basic principles of hematologic assays, incl. good laboratory practice. Student is able to: -indentify basic types of blood elements of peripheral blood and bone marrow, -interpret findings CBC blood count, -provide basic coagulation assays, -interpret basic coagulation tests.
- Syllabus
- Origin and development of blood cells.
- Basic principles of blood coagulation.
- Plasmatic clotting factors, their physiology. Inherited bleeding disorders.
- Primary hemostasis, platelet plug formation and its abnormalities.
- Basic principles of anti-platelet therapy.
- Inherited thrombophilias, anti-thrombotic treatment and its monitoring.
- Acquired disorders of blood clotting.
- Red cell disorders.
- Myeloproliferative neoplasms.
- Acute leukaemias.
- Myelodyspastic syndrome.
- Lymphoproliferative disorders.
- Flow cytometry and molecular genetic assays for diagnosis of hematology diseases.
- Therapeutic aphaeresis, basic principles of hemopoietic cells transplantation.
- Literature
- PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie krevní buňky. 1. vyd. Český Těšín: FINIDR, 2006, 304 s. ISBN 8086682021. info
- PECKA, Miroslav. Laboratorní hematologie v přehledu : fyziologie a patofyziologie hemostázy. 1. vyd. Český Těšín: FINIDR, 2004, 237 s. ISBN 808668203X. info
- PECKA, Miroslav. Přehled laboratorní hematologie. Bílá krevní řada, krevní destičky. [1. vyd.]. Praha: Galén, 1996, 132 s. ISBN 8085824434. info
- Přehled laboratorní hematologie 1 :Krvetvorba. Červená krevní řada. Edited by Miroslav Pecka. [1. vyd.]. Praha: Galén, 1995, 141 s. ISBN 80-85824-28-0. info
- Teaching methods
- Students will attend two hours long lecture ones a week (14 per semester). Participation in lectures is optional. Each lecture is in the current version published on is.muni.cz.
- Assessment methods
- The course is closed by an examination which is divided into practical and an oral part. Practical part includes testing of haemostaseology or hematologic morphology, depending on the selected question. In the haemostaseology student performs basic coagulation test, interprets coagulation laboratory finding (four basic coagulation tests) and orally answers the selected question which is aimed at understanding the laboratory investigations in blood clotting. If the question is chosen from the morphological laboratory, the student evaluates 6 microscopic findings (in digital processing) and orally answers the selected question which is aimed at understanding the laboratory investigations in morphological diagnosis in haematology. In oral part student elects three questions, one of which is focused on non - oncological haematology, the second one concerns the blood coagulation and the third one at haematological oncology. Each question (one practical and three theoretical) is grades A-F. No grade F is necessary condition for passing an examination.
- Language of instruction
- Czech
- Further Comments
- The course is taught annually.
- Listed among pre-requisites of other courses
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/sci/autumn2024/Bi0311