Bi6727 Immunopathology

Faculty of Science
Spring 2024
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Teacher(s)
MVDr. Mgr. Monika Dušková, Ph.D. (lecturer)
doc. RNDr. Milan Číž, Ph.D. (lecturer)
Guaranteed by
MVDr. Mgr. Monika Dušková, Ph.D.
Department of Experimental Biology – Biology Section – Faculty of Science
Contact Person: MVDr. Mgr. Monika Dušková, Ph.D.
Supplier department: Department of Experimental Biology – Biology Section – Faculty of Science
Timetable
Mon 19. 2. to Sun 26. 5. Thu 8:00–9:50 B11/333
Prerequisites
Bi5220 Immunology
basic course immunology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The course continues in the basic training in immunology and develops knowledge in recognition of pathology statuses of immune system. Special attention is paid to processes involved in mechanisms of initiation of the pathology, diagnostics, symptoms and therapeutic opportunities.
At the end of the course students should be able to:
understand end explain physiological mechanisms involved in immune system;
differentiate the primary and secondary immunodeficiency;
define interactions of selected infection factors with immune system;
characterize immunological mechanisms of selected tissues and organ systems, hypersensitivity, transplantation immunology, reproductive immunology, and autoimmune diseases.
Learning outcomes
Student’s skills after passing the exam: - knowledge on basic immune-pathologic grades (immune-deficiency – primary and secondary, hypersensitivity, autoimmune diseases), their pathogenesis, symptoms, diagnostics and therapy. Student will understand the immunological basis of these diseases and symptoms.
Syllabus
  • 1. Structure and physiological mechanism involved in immune system: an overview. 2. Immunity impairments: medicinal aspects, ethical and social issues. Types of diagnostics/therapeutic approaches. 3. Primary immunodeficiency: role of mutations, typology of primary deficits, incidence, pathophysiology, symptoms, diagnostics and therapy 4. Secondary immunodeficiency: causal association, mechanisms of initiation, symptoms, therapeutic opportunities. 5. Interactions of selected infection factors with immune system: (TBC, Borrelia) 6. Immunological mechanisms of selected tissues and organ systems 7. Hypersensitivity 8. Transplantation immunology 9. Reproductive immunology 10. Autoimmune diseases
Literature
  • CHAPEL, Helen, Mansel HAENEY, Siraj A. MISBAH and Neil SNOWDEN. Základy klinické imunologie : 6. vydání. Translated by Vojtěch Thon. Kroměříž: Triton, 2018, xiv, 343. ISBN 9788075533968. info
  • KREJSEK, Jan and Otakar KOPECKÝ. Klinická imunologie. 1. vyd. Hradec Králové: NUCLEUS HK, 2004, 941 s. : i. ISBN 80-86225-50-X. info
  • BARTŮŇKOVÁ, Jiřina. Imunodeficience. Vyd. 1. Praha: Grada, 2002, 228 s. ISBN 8024702444. info
  • BARTŮŇKOVÁ, Jiřina and Eva VERNEROVÁ. Imunologie a alergologie. 1. vyd. Praha: TRITON, 2002, 83 s. ISBN 8072542893. info
Teaching methods
lecture
Assessment methods
The course is finished by oral examination, based on pool of 45 questions from which students draw 2. Oral examination takes typically 30 minutes, students can prepare for the exam in 15 minutes after selection of questions.
Language of instruction
Czech
Further comments (probably available only in Czech)
Study Materials
The course is taught once in two years.
Information on the per-term frequency of the course: Vypisován pouze v sudých letech.
Information on course enrolment limitations: Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
The course is also listed under the following terms Spring 2008 - for the purpose of the accreditation, Spring 2005, Spring 2006, Spring 2007, Spring 2008, Spring 2009, Spring 2010, Spring 2012, spring 2012 - acreditation, Spring 2014, Spring 2016, spring 2018, Spring 2020, Spring 2022.
  • Enrolment Statistics (recent)
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