PřF:Bi5220 Immunology - Course Information
Bi5220 ImmunologyFaculty of Science
- Extent and Intensity
- 2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
- RNDr. Milan Číž, Ph.D. (lecturer)
doc. Mgr. Lukáš Kubala, Ph.D. (lecturer)
doc. RNDr. Antonín Lojek, CSc. (alternate examiner)
- doc. Mgr. Lukáš Kubala, Ph.D.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: doc. Mgr. Lukáš Kubala, Ph.D.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
- Mon 17. 9. to Fri 14. 12. Mon 12:00–13:50 A22/116 aula
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- Fields of study the course is directly associated with
- Ecological and Evolutionary Biology (programme PřF, B-EB)
- Ecological and Evolutionary Biology (programme PřF, B-EB, specialization Zoology)
- Special Biology (programme PřF, B-EXB)
- Special Biology (programme PřF, B-EXB, specialization Experimental Biology of Animals and Immunology)
- Special Biology (programme PřF, B-EXB, specialization Mikrobiology a Molecular Biotechnology)
- Course objectives
- At the end of the course students should be able to:
understand basic principles of immunology;
explain principles of immune response, immunoregulation, and immunomodulation;
differentiate mechanisms of hypersensitivity;
define the role of cytokines and immunomodulators;
explain mechanisms of antiinfection immunity.
- 1. Introduction to immunobiology. 2.Cells and organs of the immunity - ontogenesis, phenotype, structure, function and activation, signal receptors: 3.Immune response: antigens, structure, chemical properties, classification, presentation, MHC structure, function, regulation, immunogenetics: gene displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes T-cell receptors: structure, function and antigen binding, interaction of receptors with ligands: adhesive molecules, complement receptors, Fc receptors, transfer of signals Nonspecific immunity: complement: structure and function, acute phase reactants, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 4.The mechanism of the hypersensitivity: IgE mediated / early and late response; IgG, IgA and IgM mediated; immune complexes mediated; cell mediated. 5. Cytokines and immunomodulators: cytokines: properties, origin, structure, effect, receptor-place of effect, metabolism, regulation and gene activation. Inflammatory mediators: origin, structure, effect, receptor-place of effect, metabolism and regulation 6.Immunoregulation: toleration, clonal selection, inhibition, antigenic paralytic intracellular - interaction: help and inhibition (suppression). Idiotype network: inhibition and stimulation. Mechanisms of auto-immunity 7. Antiinfection immunity: immunity against viruses, bacteria, fungi, parasites. 8. Failures of host defence mechanisms, primary and secondary immunodeficiencies. 9. Immunity and cancer, transplantation immunology, immunotoxicology 10.Immunomodulation 11. Methods used in immunology.
- HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 2.vyd. Praha: Triton, 2002. 260 pp. ISBN 80-7254-215-X. info
- TOMAN, Miroslav. Veterinární imunologie. 1. vyd. Praha: Grada, 2000. 413 s. ISBN 8071697273. info
- Immunobiology : the immune system in health and disease. Edited by Charles Janeway. 6th ed. New York, N.Y.: Garland Science, Taylor & Francis Group, 2005. xxiii, 823. ISBN 0815341016. info
- KREJSEK, Jan and Otakar KOPECKÝ. Klinická imunologie. 1. vyd. Hradec Králové: NUCLEUS HK, 2004. 941 s. ISBN 808622550X. info
- Teaching methods
- Lectures and presentations by specialists in the individual sectors of immunology.
- Assessment methods
- Written examination which consists of 12 questions. It is necessary to obtain at least 16 points (maximum 30 points) for successful passing.
- Language of instruction
- Further comments (probably available only in Czech)
- The course is taught annually.
Information on course enrolment limitations: Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
- Listed among pre-requisites of other courses
- Bi5220c Immunology - practical course
- Bi8250 Developmental and Comparative Immunology
- Bi8250c Developmental and Comparative Immunology - practical course
- Bi9250 Special Immunological Methods
- Bi9350 Immunogenetics and immunogenomics
Bi3060 && (Bi4010 || Bi4020) && Bi5220 && Bi7250
- Bi9901 Free radicals in animal physiology
Bi3030 && (Bi5220 || Bi6930)
- Bi5220c Immunology - practical course
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/sci/autumn2018/Bi5220