PřF:Bi5220 Immunology - Course Information
Bi5220 ImmunologyFaculty of Science
- Extent and Intensity
- 2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
- doc. RNDr. Milan Číž, Ph.D. (lecturer)
doc. Mgr. Lukáš Kubala, Ph.D. (lecturer)
doc. RNDr. Antonín Lojek, CSc. (alternate examiner)
- Guaranteed by
- doc. Mgr. Lukáš Kubala, Ph.D.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: doc. Mgr. Lukáš Kubala, Ph.D.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
- Mon 13:00–14:50 B11/132
- Prerequisites (in Czech)
- ! Bi5220en Immunology && ! NOWANY ( Bi5220en Immunology )
- Course Enrolment Limitations
- The course is also offered to the students of the fields other than those the course is directly associated with.
- fields of study / plans the course is directly associated with
- there are 10 fields of study the course is directly associated with, display
- Course objectives
- At the end of the course students should be able to:
understand basic principles of immunology;
explain principles of immune response, immunoregulation, and immunomodulation;
differentiate mechanisms of hypersensitivity;
define the role of cytokines and immunomodulators;
explain mechanisms of anti-infection immunity.
- Learning outcomes
- Student will be able to:
- to identify and describe the individual components of the immune system of humans and selected mammals;
- to describe the functions of cellular immune response;
- to describe the functions of the humoral immune response;
- to compare and highlight differences in non-specific and specific immune response;
- to compare and highlight differences in the principles of immune response to various pathogens and damaged or altered own cells;
- to describe current scientific knowledge in the field of pathological disorders of the immune system;
- 1. Introduction to immunobiology. 2.Cells and organs of the immunity - ontogenesis, phenotype, structure, function and activation, signal receptors: 3.Immune response: antigens, structure, chemical properties, classification, presentation, MHC structure, function, regulation, immunogenetics: gene displacement, polymorphism, genesis of diversity Antibodies: structure, chemical properties, functions, classes of antibodies, isotypes, allotypes, idiotypes T-cell receptors: structure, function and antigen binding, interaction of receptors with ligands: adhesive molecules, complement receptors, Fc receptors, transfer of signals Nonspecific immunity: complement: structure and function, acute phase reactants, inflammation Phagocytosis: phases, cooperation of the phagocytosis with other components of the immune system 4.The mechanism of the hypersensitivity: IgE mediated / early and late response; IgG, IgA and IgM mediated; immune complexes mediated; cell mediated. 5. Cytokines and immunomodulators: cytokines: properties, origin, structure, effect, receptor-place of effect, metabolism, regulation and gene activation. Inflammatory mediators: origin, structure, effect, receptor-place of effect, metabolism and regulation 6.Immunoregulation: toleration, clonal selection, inhibition, antigenic paralytic intracellular - interaction: help and inhibition (suppression). Idiotype network: inhibition and stimulation. Mechanisms of auto-immunity 7. Antiinfection immunity: immunity against viruses, bacteria, fungi, parasites. 8. Failures of host defence mechanisms, primary and secondary immunodeficiencies. 9. Immunity and cancer, transplantation immunology, immunotoxicology 10.Immunomodulation 11. Methods used in immunology.
- Immunobiology : the immune system in health and disease. Edited by Charles Janeway. 6th ed. New York, N.Y.: Garland Science, Taylor & Francis Group, 2005. xxiii, 823. ISBN 0815341016. info
- HOŘEJŠÍ, Václav and Jiřina BARTŮŇKOVÁ. Základy imunologie. 2.vyd. Praha: Triton, 2002. 260 pp. ISBN 80-7254-215-X. info
- TOMAN, Miroslav. Veterinární imunologie. 1. vyd. Praha: Grada, 2000. 413 s. ISBN 8071697273. info
- KREJSEK, Jan and Otakar KOPECKÝ. Klinická imunologie. 1. vyd. Hradec Králové: NUCLEUS HK, 2004. 941 s. ISBN 808622550X. info
- Teaching methods
- Assessment methods
- Written examination which consists of 12 questions. It is necessary to obtain at least 16 points (maximum 30 points) for successful passing.
- Language of instruction
- Follow-Up Courses
- Further comments (probably available only in Czech)
- The course is taught annually.
Information on course enrolment limitations: Na předmět se vztahuje povinnost registrace, bez registrace může být znemožněn zápis předmětu!
- Listed among pre-requisites of other courses
- Bi5220c Immunology - practical course
Bi5220 || Bi5220en
- Bi5220en Immunology
(!Bi5220) && (!NOWANY(Bi5220)) && (program(M137) || (souhlas))
- Bi6384 Advanced and Applied Immunology
- Bi8250 Developmental and Comparative Immunology
- Bi8250c Developmental and Comparative Immunology - practical course
- Bi9250 Special Immunological Methods
- Bi9250c Special Immunological Methods - practical course
Bi5220 && Bi5220c
- Bi9350 Immunogenetics and immunogenomics
Bi3060 && (Bi4010 || Bi4020) && Bi5220
- Bi9901 Free radicals in animal physiology
Bi3030 && Bi5220
- Bi5220c Immunology - practical course
- Enrolment Statistics (recent)
- Permalink: https://is.muni.cz/course/sci/autumn2022/Bi5220