Bi4010 Essential molecular biology

Faculty of Science
Spring 2022
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
Taught in person.
Teacher(s)
prof. RNDr. Jiří Doškař, CSc. (lecturer)
doc. RNDr. Roman Pantůček, Ph.D. (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Jan Šmarda, CSc.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
Timetable
Mon 15:00–16:50 B11/132
Prerequisites
! Bi4020 Molecular biology
Basic knowledge of general zoology and botany, microbiology, genetics, physiology, organic chemistry and biochemistry.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 15 fields of study the course is directly associated with, display
Course objectives
This lecture is conceived as an introduction into molecular biology and it provides explanation of basic cell processes on molecular level. Structure of genome, principles of gene expression, internal cell organization and its behaviour in the context of unicellular multicellular organisms are the main topics of the lecture. At the end of the course, the student will be able understand and discuss molecular principles driving cellular behaviour on basic level.
Learning outcomes
At the end of the course, the student will be able understand and discuss molecular principles driving cellular behaviour on basic level.
Syllabus
  • 1. Genesis of molecular biology, milestones, main model systems. 2. Structure and function of DNA, chromosomal DNA and its packaging in the chromatin fiber, characteristic of genes and genomes. 3. DNA replication. 4. Mechanisms of transcription, splicing, DNA editing. 5. Translation and posttranslation processing of proteins 7. Control of gene expression, regulatory proteins, genetic switches, post-transcriptional controls, RNA interference. 8. Mutations and DNA repair mechanisms 9. DNA recombination, and transposition 10. Genetic mobile elements, transposition of DNA 11. Molecular basis of immune system in animals 12. Gene engeneering - the basic principles
Literature
    required literature
  • SNUSTAD, D. Peter and Michael J. SIMMONS. Genetika. Edited by Jiřina Relichová. Druhé, aktualizované vydá. Brno: Masarykova univerzita, 2017. xix, 844. ISBN 9788021086135. info
    recommended literature
  • ALBERTS, Bruce. Essential cell biology. 2nd ed. New York: Garland Science, 2004. xxi, 740. ISBN 0815334818. info
  • ROSYPAL, Stanislav, Jiří DOŠKAŘ, Roman PANTŮČEK, Jana KAILEROVÁ, Jiřina RELICHOVÁ, Vladislava RŮŽIČKOVÁ, Jan ŠMARDA, Jan ŠMARDA and Jiří ŠTĚPÁN. TERMINOLOGIE MOLEKULÁRNÍ BIOLOGIE. České odborné termíny, definice a anglické ekvivalenty (Terminology of molecular biology). První vydání. Brno: Vydavatel Prof. RNDr. Stanislav Rosypal, DrSc. Vodova 80, 612 00 Brno, 2001. 300 pp. ISBN 80-902562-3-6. URL info
Teaching methods
lectures follwed by brief discussions
Assessment methods
Written test is required. At least 50% of correct answers is required to pass the exam. Oral examination can be used to specify classification.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
Study Materials
The course is taught annually.
General note: Studenti profilující své studium směrem k využití molekulárně biologických metod si mohou namísto předmětu Bi4010 zapsat jednu z dvojic předmětů Bi4020 + Bi4020c nebo Bi4020 + Bi4035, která jim bude uznána jakožto předmětový ekvivalent Bi4010.
Listed among pre-requisites of other courses

Zobrazit další předměty

The course is also listed under the following terms Spring 2011 - only for the accreditation, Spring 2009, Spring 2010, Spring 2011, Spring 2012, spring 2012 - acreditation, Spring 2013, Spring 2014, Spring 2015, Spring 2016, Spring 2017, spring 2018, Spring 2019, Spring 2020, Spring 2021, Spring 2023.
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