Bi7150 Mechanisms of Microevolution

Faculty of Science
Spring 2022
Extent and Intensity
2/0/0. 2 credit(s) (fasci plus compl plus > 4). Type of Completion: zk (examination).
prof. RNDr. Miloš Macholán, CSc. (lecturer)
Guaranteed by
prof. RNDr. Miloš Macholán, CSc.
Department of Botany and Zoology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Miloš Macholán, CSc.
Supplier department: Department of Botany and Zoology - Biology Section - Faculty of Science
Bi3060 Basic genetics && Bi4010 Essential molecular biology
Completion of Bi8150 Evolutionary Biology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
This course should render basic information on the genetic structure of natural populations as well as on underlying evolutionary mechanisms and processes. It is designed both as an extension of Evolutionary Biology and as a prerequisity for the follow-up Molecular Ecology.
Learning outcomes
The graduate will be able to understand basic principles of evolutionary mechanisms acting on the population level as a footing for practical uasage of up-to-date molecular-genetic methods of analysis of genetic variation in natural populations.
  • 1. Genetic variation in natural populations: Hardy-Weinberg principle, linkage disequilibrium
  • 2. Sources of variation: mutation, recombination, gene flow, non-random mating
  • 3. Natural selection
  • 4. Interactions of selection and other evolutionary forces, balancing selection
  • 5. Random processes in populations
  • 6. Molecular evolution
  • 7. Principles of quantitative genetics
    recommended literature
  • NIELSEN, Rasmus and Montgomery SLATKIN. An introduction to population genetics : theory and applications. Sunderland: Sinauer Associates, 2013. xii, 287. ISBN 9781605351537. info
  • HARTL, Daniel L. and Andrew G. CLARK. Principles of population genetics. 4th ed. Sunderland, Mass.: Sinauer Associates, 2007. xv, 652. ISBN 9780878933082. info
  • TEMPLETON, Alan Robert. Population genetics and microevolutionary theory. 1st ed. Hoboken: John Wiley & Sons, 2006. x, 705. ISBN 9780471409519. info
Teaching methods
Assessment methods
oral exam
Language of instruction
Follow-Up Courses
Further Comments
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2014, Autumn 2015, Autumn 2016, spring 2018, Spring 2019, Spring 2020, Spring 2021.
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