B4030 Molecular biology

Faculty of Science
Spring 2002
Extent and Intensity
4/0/0. 6 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Stanislav Rosypal, DrSc. (lecturer), doc. RNDr. Roman Pantůček, Ph.D. (deputy)
RNDr. Jana Kailerová, CSc. (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Stanislav Rosypal, DrSc.
Prerequisites (in Czech)
! B4020 Molecular biology && ! B7940 Molecular biology
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
Proteins (primary, secondary and higher structures of proteins and their biological functions). Nucleic acids (primary, secondary and tertiary structure of DNA and RNA, different conformations of DNA and their significance in biological systems). Interactions of proteins with DNA. Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication of procaryotic and eucaryotic genome. Transcription of procaryotic and eucaryotic genome. Postranscriptional modification and processing of RNA, especially in eucaryotes. Mechanisms of splicing and selfsplicing. Translation of procaryotic and eucaryotic mRNA. Posttranslational processing. Regulation of gene expression in procaryotes and eucaryotes. Signal pathways in mammal cells and their relation to the activation of transcription factors. Molecular basis of acquired immunity. Molecular basis of cancerogenesis (oncogenes, antioncogenes). Mechanisms of replication of viral DNA and RNA, transcription of viral DNA and translation of viral RNA. Molecular mechanisms of mutagenesis and recombination. Transposons. Repair mechanisms of damaged DNA. Elements of molecular evolution. Origin of life from the aspects of molecular biology. On the whole, the general molecular processes occuring in living systems are emphasized in this lecture with respect to the specificities characteristic of the main groups of living systems (bacteria, archea, plants, animals and viruses).
Language of instruction
Czech
Follow-Up Courses
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2000, Spring 2001.
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