B4020 Molecular biology

Faculty of Science
Spring 2002
Extent and Intensity
4/3/0. 8 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Stanislav Rosypal, DrSc. (lecturer), doc. RNDr. Roman Pantůček, Ph.D. (deputy)
doc. RNDr. Roman Pantůček, Ph.D. (seminar tutor)
doc. RNDr. Vladislava Růžičková, CSc. (seminar tutor)
RNDr. Jana Kailerová, CSc. (assistant)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Stanislav Rosypal, DrSc.
Timetable of Seminar Groups
B4020/01: No timetable has been entered into IS. R. Pantůček
B4020/02: No timetable has been entered into IS. R. Pantůček
B4020/03: No timetable has been entered into IS. V. Růžičková
B4020/04: No timetable has been entered into IS. V. Růžičková
Prerequisites
! B4030 Molecular biology && ! B7940 Molecular biology
Basic knowledge of general zoology and botany, microbiology, genetics, physiology, organic chemistry and biochemistry.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
there are 13 fields of study the course is directly associated with, display
Course objectives
This lecture is conceived as an introduction into molecular biology and is based on the chapters selected from the textbook "Introduction into Molecular Biology" (1999-2000, four parts). It gives the explanation of processes on molecular level in relation to the basic functions of living systems (procaryotic as well as eucaryotic organisms and viruses). On the whole, the general molecular processes occuring in living systems are emphasized in this lecture with respect to the specificities characteristic of the main groups of living systems (bacteria, archea, plants, animals and viruses)
Syllabus
  • Proteins (primary, secondary and higher structures of proteins and their biological functions). Nucleic acids (primary, secondary and tertiary structure of DNA and RNA, different conformations of DNA and their significance in biological systems). Interactions of proteins with DNA. Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication of procaryotic and eucaryotic genome. Transcription of procaryotic and eucaryotic genome. Postranscriptional modification and processing of RNA, especially in eucaryotes. Mechanisms of splicing and selfsplicing. Translation of procaryotic and eucaryotic mRNA. Posttranslational processing. Regulation of gene expression in procaryotes and eucaryotes. Signal pathways in mammal cells and their relation to the activation of transcription factors. Molecular basis of acquired immunity. Molecular basis of cancerogenesis (oncogenes, antioncogenes). Mechanisms of replication of viral DNA and RNA, transcription of viral DNA and translation of viral RNA. Molecular mechanisms of mutagenesis and recombination. Transposons. Repair mechanisms of damaged DNA. Elements of molecular evolution. Origin of life from the aspects of molecular biology. Essentials of molecular evolution. Origin of life from the aspects of molecular biology. On the whole, the general molecular processes occuring in living systems are emphasized in this lecture with respect to the specificities characteristic of the main groups of living systems (bacteria, archea, plants, animals and viruses).
Literature
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 1998. 300 pp. Díl I. Informační makromolekuly. ISBN 80-902562-0-1. URL info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 1999. 300 pp. Díl II. Molekulární biologie eukaryot. ISBN 80-902562-1-X. URL info
  • ROSYPAL, Stanislav. Úvod do molekulární biologie. Třetí inovované vydání. Brno, 2000. 300 pp. Díl III. Molekulární biologie virů. ISBN 80-902562-2-8. URL info
Assessment methods (in Czech)
Přednáška spojená s diskusí. Zkouška testem.
Language of instruction
Czech
Follow-Up Courses
Further comments (probably available only in Czech)
The course is taught annually.
Listed among pre-requisites of other courses
The course is also listed under the following terms Spring 2000, Spring 2001.
  • Enrolment Statistics (recent)
  • Permalink: https://is.muni.cz/course/sci/spring2002/B4020