B7940 Molecular biology

Faculty of Science
Autumn 2001
Extent and Intensity
3/0/5. 8 credit(s). Type of Completion: zk (examination).
prof. RNDr. Jiří Doškař, CSc. (lecturer)
prof. RNDr. Roman Pantůček, Ph.D. (seminar tutor)
Guaranteed by
prof. RNDr. Jiří Doškař, CSc.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: prof. RNDr. Jiří Doškař, CSc.
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
History of molecular biology. Information macromolecules (proteins, nucleic acids). Genetic information, genetic code. Molecular structure and organization of cellular and viral genome. The main types of nucleotide sequences in genomes. Replication of prokaryotic, eukaryotic and viral genome. Transcription of genetic information. Structure of promotors and enhancers, transcription activators. Splicing, selfsplicing, editing hnRNA. Translation of genetic information (transfer RNA, activation of amino acids, ribosomes). Regulation of gene expression in prokaryotes and eukaryotes. Molecular basis of mutation and recombination. DNA repair. Restriction and modification of DNA. Prokaryotic and eukaryotic transposable elements. Basic methods of molecular genetics and gene engineering. Transgenic organisms. Gene therapy. Application of recombinant DNA to biotechnology.
Language of instruction
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 1999, Autumn 2000.
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