Bi5220en Immunology

Faculty of Science
Autumn 2022
Extent and Intensity
2/0/0. 2 credit(s) (plus extra credits for completion). Type of Completion: zk (examination).
Taught in person.
doc. RNDr. Milan Číž, Ph.D. (lecturer)
doc. Mgr. Lukáš Kubala, Ph.D. (lecturer)
Guaranteed by
doc. Mgr. Lukáš Kubala, Ph.D.
Department of Experimental Biology - Biology Section - Faculty of Science
Contact Person: doc. RNDr. Martin Vácha, Ph.D.
Supplier department: Department of Experimental Biology - Biology Section - Faculty of Science
Thu 10:00–11:50 D36/209
(! Bi5220 Immunology ) && (! NOWANY ( Bi5220 Immunology )) && ( PROGRAM ( M137 ) || ( SOUHLAS ))
During the course all necessary information will be provided. However, basic knowledge of animal physiology or biochemistry is welcome.
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
The general aim of the course is that students will achieve a basic knowledge in immunobiology and clinical immunology. The immune system of vertebrates, namely humans, will be emphasized.
Learning outcomes
On completion of the course, students will be able to understand basic principles of immunology; explain principles of innate and adaptive immune response, immunoregulation, and immunomodulation; define the role of individual constituents of the immune system and its mediators in immune response to infection; and understand the basic principles of immune system pathology and the role of immune system in transplantation and cancer.
  • 1. Introduction to immunes system, basic terms and history of immunology.
  • 2. Cells and organs of the immune system.
  • 3. Phagocytes, inflammation, complement.
  • 4. Antigens, major histocompatibility complex, antigen presentation.
  • 5. Origin and development of T- and B-lymphocytes.
  • 6. Antibodies, their characteristics and functions.
  • 7. Cell communication in immune system.
  • 8. Cytokines.
  • 9. Infectious diseases, immunity against viruses, bacteria, fungi, and parasites.
  • 10. Autoimmunity, primary and secondary immunodeficiencies.
  • 11. Allergy and hypersensitivity.
  • 12. Immunomodulation, vaccination.
  • 13. Transplantation and cancer immunology.
  • 14. Methods used in immunology.
  • MURPHY, Kenneth, Casey WEAVER, Allan MOWAT, Leslie BERG and David CHAPLIN. Janeway's immunobiology / Kenneth Murphy, Casey Weaver ; with contributions by Allan Mowat, Leslie Berg, David Chaplin. 9th edition. New York: Garland Science, 2016. xx, 904. ISBN 9780815345053. info
Teaching methods
The principal learning activity during the course will be lectures, supported with studying recommended basic immunology literature.
Assessment methods
Written exam consisting of 12 questions evaluated by max. 30 points, min. 16 points are needed to pass.
Language of instruction
Further comments (probably available only in Czech)
The course is taught annually.
Information on course enrolment limitations: The course is offered to incoming Erasmus students of biological and biochemical programs.
Listed among pre-requisites of other courses
The course is also listed under the following terms Autumn 2019, Autumn 2020, autumn 2021.
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