C7530 Physiology of Cell Systems

Faculty of Science
Autumn 2001
Extent and Intensity
2/0/0. 2 credit(s). Type of Completion: zk (examination).
Teacher(s)
prof. RNDr. Jiřina Hofmanová, CSc. (lecturer)
prof. RNDr. Alois Kozubík, CSc. (lecturer)
Guaranteed by
prof. RNDr. Alois Kozubík, CSc.
Chemistry Section – Faculty of Science
Contact Person: prof. RNDr. Ladislav Dušek, Ph.D.
Prerequisites
Basic knowledge of biochemistry, cell and molecular biology are neccessary
Course Enrolment Limitations
The course is also offered to the students of the fields other than those the course is directly associated with.
fields of study / plans the course is directly associated with
there are 6 fields of study the course is directly associated with, display
Course objectives
Complex course is aimed at a deeper understanding of cell functions, development and control of cytokinetics (proliferation, differentiation and apoptosis), and the mechanisms of action of hormones, cytokines and other regulatory molecules. A special attention is paid to the processes taking place at the level of plasmatic membrane, cytosol and nucleus, i.e. signal transduction at the molecular level. The information provided should help to understand the feedback mechanisms and the outcomes of disruptions of cellular regulation in the whole organism - reactions such as stress, inflammation, carcinogenesis. This is aimed to knowledge of mutual relationships on various regulation levels of mammalian organism (from molecules to the whole system).
Syllabus
  • 1. Introduction to theory of the systems 2. Cell population types 3. Regulation of cytokinetics Cell cycle and its regulation Growth stimulators and inhibitors 4. Structure and function of cell membranes Lipid mediators and cytokines Signal transduction and expression of genetic information Hematopoietic system and its functions Membrane recognition and immune systems 6. Homeostasis, health and disease Organism as hierarchic systém Cooperation of nervous, endocrine and humoral systems 7. Harmful environmental factors and human health risk
Literature
  • TROJAN, Stanislav. Lékařská fyziologie. Vyd. 3., dopl. a rozš. Praha: Grada, 1999, 612 s. ISBN 8071697885. info
  • Cell Physiology Source Book, ed. N. Sperelakis, Academic Press Inc., 1995
  • ALBERTS, Bruce. Molecular biology of the cell. 3rd ed. New York: Garland Publishing, Inc., 1994, xliii, 129. ISBN 0-8153-1620-8. info
  • VOET, Donald and Judith G. VOET. Biochemie. Translated by Arnošt Kotyk. 1. vyd. Praha: Victoria Publishing, 1995, S. II-XIV,. ISBN 80-85605-44-9. info
  • Molecular cell biology. Edited by James Darnell - Harvey Lodish - D. Baltimore. 2nd ed. New York: Scientific American Books, 1990, x, 1105 s. ISBN 0-7167-2078-7. info
  • J. Neuwirt, E. Nečas: Kmenové buňky a krevní choroby, Avicenum Praha 1981
  • ŠTERZL, Jaroslav. Imunitní systém a jeho fyziologické funkce. Praha: Česká imunologická společnost, 1993, 480 s. info
  • KOTYK, Arnošt. Struktura a funkce biomembrán. 1. vyd. Brno: Masarykova univerzita, 1996, 173 s. ISBN 8021013168. info
  • The cytokine handbook, ed. A. W. Thompson, Academic Press New York, 1994
  • + doporučené speciální separáty a schemata z přednášek
Language of instruction
Czech
Follow-Up Courses
Further Comments
The course can also be completed outside the examination period.
The course is taught annually.
The course is taught: every week.
The course is also listed under the following terms Autumn 1999, Autumn 2000.
  • Enrolment Statistics (recent)
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