C2833 Toxicology in cultural heritage conservation

Faculty of Science
Autumn 2024
Extent and Intensity
1/0/0. 1 credit(s) (plus extra credits for completion). Type of Completion: k (colloquium).
In-person direct teaching
Teacher(s)
doc. Mgr. Karel Novotný, Ph.D. (lecturer)
prof. Ing. Miloslav Pouzar, Ph.D. (lecturer)
Ing. Mgr. Bc. Radka Kopecká, Ph.D. (assistant)
Guaranteed by
doc. Mgr. Karel Novotný, Ph.D.
Department of Chemistry – Chemistry Section – Faculty of Science
Supplier department: Department of Chemistry – Chemistry Section – Faculty of Science
Course Enrolment Limitations
The course is offered to students of any study field.
Course objectives
Course participants will learn about the basic principles of the interaction of toxic substances with the organism and the mechanisms by which these substances can harm human health, understand the relationship between the dangerousness of a toxic substance and the risk that a given substance poses to human health within a specific exposure scenario, learn about the basic sources of information about toxic substances and methods of protection against their effects. Within the discussion of selected case studies, they will become familiar with the most common groups of toxic substances threatening the health of restorers, conservators, museum workers, etc. and will learn about the possibilities of their detection and substitution for alternatives more friendly to health and the environment.
Learning outcomes
After completing the course, the student will be able to assess the level of risks of handling chemical substances in the field of cultural heritage care.
Syllabus
  • 1) Introduction to toxicokinetics (absorption, distribution, biotransformation and excretion of a toxic substance)
  • 2) Introduction to toxicodynamics – effects of substances at the organ level (hematotoxic, pulmotoxic, neurotoxic, dermatotoxic, immunotoxic, etc.)
  • 3) Introduction to risk analysis – dangerousness and risk of toxic substances, methods of defining and controlling limits for toxic substances in the work environment, information sources
  • 4) Selected groups of toxic substances I – toxic metals, inorganic pigments and other types of preparations based on inorganic compounds
  • 5) Selected groups of toxic substances II - solvents, cleaners, biocides, dyes, synthetic resins and other types of preparations based on organic substances
  • 6) Selected groups of toxic substances III – toxins, wood dust, pollen and other toxic substances of natural origin
Literature
  • LINHART, Igor. Toxikologie : interakce škodlivých látek s živými organismy, jejich mechanismy, projevy a důsledky. 3. upravené a rozšířené. Praha: Vysoká škola chemicko-technologická v Praze, 2022, 411 stran. ISBN 9788075921031. info
  • Prokeš, J. Základy toxikologie. GALÉN Praha, 2005. ISBN 80-7262-301-X. info
Teaching methods
lectures and class discussion
Assessment methods
k filling in questionary
Language of instruction
Czech
Further Comments
Study Materials
The course is taught annually.
The course is also listed under the following terms Autumn 2023, Autumn 2025.
  • Enrolment Statistics (Autumn 2024, recent)
  • Permalink: https://is.muni.cz/course/sci/autumn2024/C2833