| DIVIŠOVÁ, Šárka, Eva VLČKOVÁ, Mária HNOJČÍKOVÁ, Miroslav ŠKORŇA, Martin NĚMEC, Petr DUBOVÝ, Ladislav DUŠEK, Jiří JARKOVSKÝ, Jana BĚLOBRÁDKOVÁ a Josef BEDNAŘÍK. Prediabetes/early diabetes-associated neuropathy predominantly involves sensory small fibres. Journal of the Peripheral Nervous System. Hoboken, USA: WILEY-BLACKWELL, 2012, roč. 17, č. 3, s. 341-350. ISSN 1085-9489. Dostupné z: https://dx.doi.org/10.1111/j.1529-8027.2012.00420.x. |
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@article{1074303,
author = {Divišová, Šárka and Vlčková, Eva and Hnojčíková, Mária and Škorňa, Miroslav and Němec, Martin and Dubový, Petr and Dušek, Ladislav and Jarkovský, Jiří and Bělobrádková, Jana and Bednařík, Josef},
article_location = {Hoboken, USA},
article_number = {3},
doi = {http://dx.doi.org/10.1111/j.1529-8027.2012.00420.x},
keywords = {diabetic neuropathy; prediabetes; small-fibre neuropathy; subclinical neuropathy; type 2 diabetes mellitus},
language = {eng},
issn = {1085-9489},
journal = {Journal of the Peripheral Nervous System},
title = {Prediabetes/early diabetes-associated neuropathy predominantly involves sensory small fibres},
url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1529-8027.2012.00420.x/abstract;jsessionid=ACC2AEE4796DC27669E2D4B624D02919.d03t04},
volume = {17},
year = {2012}
}
TY - JOUR
ID - 1074303
AU - Divišová, Šárka - Vlčková, Eva - Hnojčíková, Mária - Škorňa, Miroslav - Němec, Martin - Dubový, Petr - Dušek, Ladislav - Jarkovský, Jiří - Bělobrádková, Jana - Bednařík, Josef
PY - 2012
TI - Prediabetes/early diabetes-associated neuropathy predominantly involves sensory small fibres
JF - Journal of the Peripheral Nervous System
VL - 17
IS - 3
SP - 341-350
EP - 341-350
PB - WILEY-BLACKWELL
SN - 10859489
KW - diabetic neuropathy
KW - prediabetes
KW - small-fibre neuropathy
KW - subclinical neuropathy
KW - type 2 diabetes mellitus
UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1529-8027.2012.00420.x/abstract;jsessionid=ACC2AEE4796DC27669E2D4B624D02919.d03t04
L2 - http://onlinelibrary.wiley.com/doi/10.1111/j.1529-8027.2012.00420.x/abstract;jsessionid=ACC2AEE4796DC27669E2D4B624D02919.d03t04
N2 - The aim of this study was to investigate the characteristics of prediabetes (preDM) and early (less than 3 years) diabetes mellitus type 2 (eDM2)-associated neuropathy and the value of recently proposed diagnostic criteria for diabetic sensorimotor polyneuropathy (DSPN). A prospective case-control study in a group of 48 consecutive patients with eDM2, 16 preDM patients and 40 age- and sex-matched normoglycaemic controls was performed. Clinical and laboratory diagnostic tests were used to detect neuropathic abnormalities; these were further classified in terms of recent diagnostic criteria. Criteria for confirmed DSPN based on abnormal nerve conduction (NC) studies were met in 7 (14.6%) eDM2 patients compared to no control, and the proportion significantly increased to 37.5% compared to 2.5% controls, if intraepidermal nerve fibre density (IENFD) was used as an alternative criterion in addition to NC. The subclinical DSPN criteria based on NC abnormalities were met in 4.2% eDM2 patients, while the proportion of preDM and eDM2 cases with subclinical sensory small-fibre involvement documented by IENFD reached 12.5% and 22.9% compared with 2.5% controls (p = 0.005 for eDM2). The absolute IENFD values from distal leg were significantly lower in both eDM2 and preDM patients (p = 0.005) compared to controls. Neuropathy associated with preDM/eDM2 predominantly involves sensory small fibres.
ER -
DIVIŠOVÁ, Šárka, Eva VLČKOVÁ, Mária HNOJČÍKOVÁ, Miroslav ŠKORŇA, Martin NĚMEC, Petr DUBOVÝ, Ladislav DUŠEK, Jiří JARKOVSKÝ, Jana BĚLOBRÁDKOVÁ a Josef BEDNAŘÍK. Prediabetes/early diabetes-associated neuropathy predominantly involves sensory small fibres. \textit{Journal of the Peripheral Nervous System}. Hoboken, USA: WILEY-BLACKWELL, 2012, roč.~17, č.~3, s.~341-350. ISSN~1085-9489. Dostupné z: https://dx.doi.org/10.1111/j.1529-8027.2012.00420.x.
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