Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic
Yersinia Strains via YiuR-Mediated Reception, TonB Import, and
Cell Membrane Pore Formation

J 2012

Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation

BOSÁK, Juraj; Petra LAIBLOVA; Jan ŠMARDA; Daniela DĚDIČOVÁ; David ŠMAJS et al.

Základní údaje

Originální název

Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation

Autoři

BOSÁK, Juraj; Petra LAIBLOVA; Jan ŠMARDA; Daniela DĚDIČOVÁ a David ŠMAJS

Vydání

Journal of Bacteriology, WASHINGTON, AMER SOC MICROBIOLOGY, 2012, 0021-9193

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.177

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/12:00064916

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1128/JB.05885-11

UT WoS

000302180200012

Klíčová slova anglicky

HUMAN ESCHERICHIA-COLI; SON-KILLER BACTERIUM; SP-NOV; OUTER-MEMBRANE; ARSENOPHONUS-NASONIAE; SERRATIA-MARCESCENS; NUCLEOTIDE-SEQUENCE; VIRULENCE FACTOR; GENOME SEQUENCE; PESTICIN

Příznaky

Mezinárodní význam

Změněno: 21. 3. 2017 15:14, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

A novel colicin type, designated colicin F-Y, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F-Y was active against both pathogenic and nonpathogenic strains of the genus Yersinia. Plasmid YF27601 (5,574 bp) of Y. frederiksenii Y27601 was completely sequenced. The colicin F-Y activity gene (cfyA) and the colicin F-Y immunity gene (cfyI) were identified. The deduced amino acid sequence of colicin F-Y was very similar in its C-terminal pore-forming domain to colicin Ib (69% identity in the last 178 amino acid residues), indicating pore forming as its lethal mode of action. Transposon mutagenesis of the colicin F-Y-susceptible strain Yersinia kristensenii Y276 revealed the yiuR gene (ykris001_4440), which encodes the YiuR outer membrane protein with unknown function, as the colicin F-Y receptor molecule. Introduction of the yiuR gene into the colicin F-Y-resistant strain Y. kristensenii Y104 restored its susceptibility to colicin F-Y. In contrast, the colicin F-Y-resistant strain Escherichia coli TOP10F' acquired susceptibility to colicin F-Y only when both the yiuR and tonB genes from Y. kristensenii Y276 were introduced. Similarities between colicins F-Y and Ib, similarities between the Cir and YiuR receptors, and the detected partial cross-immunity of colicin F-Y and colicin Ib producers suggest a common evolutionary origin of the colicin F-Y-YiuR and colicin Ib-Cir systems.

Návaznosti

NS9665, projekt VaV

Název: Molekulární typizace bakteriocinů produkovaných kmeny Escherichia coli z klinického materiálu: identifikace kolicinů a mikrocinů v souborech komensálních a patogenních kmenů

Investor: Ministerstvo zdravotnictví ČR, Molekulární typizace bakteriocinů produkovaných kmeny Escherichia coli z klinického materiálu: identifikace kolicinů a mikrocinů v souborech komensálních a patogenních kmenů

Přiložené soubory

1950.full.pdf Verze souboru

Citovat

BOSÁK, Juraj; Petra LAIBLOVA; Jan ŠMARDA; Daniela DĚDIČOVÁ a David ŠMAJS. Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation. Journal of Bacteriology. WASHINGTON: AMER SOC MICROBIOLOGY, 2012, roč. 194, č. 8, s. 1950-1959. ISSN 0021-9193. Dostupné z: https://doi.org/10.1128/JB.05885-11.

@article{1075188,
   author = {Bosák, Juraj and Laiblova, Petra and Šmarda, Jan and Dědičová, Daniela and Šmajs, David},
   article_location = {WASHINGTON},
   article_number = {8},
   doi = {https://doi.org/10.1128/JB.05885-11},
   keywords = {HUMAN ESCHERICHIA-COLI; SON-KILLER BACTERIUM; SP-NOV; OUTER-MEMBRANE; ARSENOPHONUS-NASONIAE; SERRATIA-MARCESCENS; NUCLEOTIDE-SEQUENCE; VIRULENCE FACTOR; GENOME SEQUENCE; PESTICIN},
   language = {eng},
   issn = {0021-9193},
   journal = {Journal of Bacteriology},
   title = {Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation},
   volume = {194},
   year = {2012}
}

TY  - JOUR
ID  - 1075188
AU  - Bosák, Juraj - Laiblova, Petra - Šmarda, Jan - Dědičová, Daniela - Šmajs, David
PY  - 2012
TI  - Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation
JF  - Journal of Bacteriology
VL  - 194
IS  - 8
SP  - 1950-1959
EP  - 1950-1959
PB  - AMER SOC MICROBIOLOGY
SN  - 00219193
KW  - HUMAN ESCHERICHIA-COLI
KW  - SON-KILLER BACTERIUM
KW  - SP-NOV
KW  - OUTER-MEMBRANE
KW  - ARSENOPHONUS-NASONIAE
KW  - SERRATIA-MARCESCENS
KW  - NUCLEOTIDE-SEQUENCE
KW  - VIRULENCE FACTOR
KW  - GENOME SEQUENCE
KW  - PESTICIN
N2  - A novel colicin type, designated colicin F-Y, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F-Y was active against both pathogenic and nonpathogenic strains of the genus Yersinia. Plasmid YF27601 (5,574 bp) of Y. frederiksenii Y27601 was completely sequenced. The colicin F-Y activity gene (cfyA) and the colicin F-Y immunity gene (cfyI) were identified. The deduced amino acid sequence of colicin F-Y was very similar in its C-terminal pore-forming domain to colicin Ib (69% identity in the last 178 amino acid residues), indicating pore forming as its lethal mode of action. Transposon mutagenesis of the colicin F-Y-susceptible strain Yersinia kristensenii Y276 revealed the yiuR gene (ykris001_4440), which encodes the YiuR outer membrane protein with unknown function, as the colicin F-Y receptor molecule. Introduction of the yiuR gene into the colicin F-Y-resistant strain Y. kristensenii Y104 restored its susceptibility to colicin F-Y. In contrast, the colicin F-Y-resistant strain Escherichia coli TOP10F' acquired susceptibility to colicin F-Y only when both the yiuR and tonB genes from Y. kristensenii Y276 were introduced. Similarities between colicins F-Y and Ib, similarities between the Cir and YiuR receptors, and the detected partial cross-immunity of colicin F-Y and colicin Ib producers suggest a common evolutionary origin of the colicin F-Y-YiuR and colicin Ib-Cir systems.
ER  -

BOSÁK, Juraj; Petra LAIBLOVA; Jan ŠMARDA; Daniela DĚDIČOVÁ a David ŠMAJS. Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation. \textit{Journal of Bacteriology}. WASHINGTON: AMER SOC MICROBIOLOGY, 2012, roč.~194, č.~8, s.~1950-1959. ISSN~0021-9193. Dostupné z: https://doi.org/10.1128/JB.05885-11.

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