Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic
Yersinia Strains via YiuR-Mediated Reception, TonB Import, and
Cell Membrane Pore Formation

J 2012

Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation

BOSÁK, Juraj, Petra LAIBLOVA, Jan ŠMARDA, Daniela DĚDIČOVÁ, David ŠMAJS et. al.

Základní údaje

Originální název

Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation

Autoři

BOSÁK, Juraj (703 Slovensko, garant, domácí), Petra LAIBLOVA (203 Česká republika), Jan ŠMARDA (203 Česká republika, domácí), Daniela DĚDIČOVÁ (203 Česká republika) a David ŠMAJS (203 Česká republika, domácí)

Vydání

Journal of Bacteriology, WASHINGTON, AMER SOC MICROBIOLOGY, 2012, 0021-9193

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.177

Kód RIV

RIV/00216224:14110/12:00064916

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1128/JB.05885-11

UT WoS

000302180200012

Klíčová slova anglicky

HUMAN ESCHERICHIA-COLI; SON-KILLER BACTERIUM; SP-NOV; OUTER-MEMBRANE; ARSENOPHONUS-NASONIAE; SERRATIA-MARCESCENS; NUCLEOTIDE-SEQUENCE; VIRULENCE FACTOR; GENOME SEQUENCE; PESTICIN

Příznaky

Mezinárodní význam

Změněno: 21. 3. 2017 15:14, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

A novel colicin type, designated colicin F-Y, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F-Y was active against both pathogenic and nonpathogenic strains of the genus Yersinia. Plasmid YF27601 (5,574 bp) of Y. frederiksenii Y27601 was completely sequenced. The colicin F-Y activity gene (cfyA) and the colicin F-Y immunity gene (cfyI) were identified. The deduced amino acid sequence of colicin F-Y was very similar in its C-terminal pore-forming domain to colicin Ib (69% identity in the last 178 amino acid residues), indicating pore forming as its lethal mode of action. Transposon mutagenesis of the colicin F-Y-susceptible strain Yersinia kristensenii Y276 revealed the yiuR gene (ykris001_4440), which encodes the YiuR outer membrane protein with unknown function, as the colicin F-Y receptor molecule. Introduction of the yiuR gene into the colicin F-Y-resistant strain Y. kristensenii Y104 restored its susceptibility to colicin F-Y. In contrast, the colicin F-Y-resistant strain Escherichia coli TOP10F' acquired susceptibility to colicin F-Y only when both the yiuR and tonB genes from Y. kristensenii Y276 were introduced. Similarities between colicins F-Y and Ib, similarities between the Cir and YiuR receptors, and the detected partial cross-immunity of colicin F-Y and colicin Ib producers suggest a common evolutionary origin of the colicin F-Y-YiuR and colicin Ib-Cir systems.

Návaznosti

NS9665, projekt VaV

Název: Molekulární typizace bakteriocinů produkovaných kmeny Escherichia coli z klinického materiálu: identifikace kolicinů a mikrocinů v souborech komensálních a patogenních kmenů

Investor: Ministerstvo zdravotnictví ČR, Molekulární typizace bakteriocinů produkovaných kmeny Escherichia coli z klinického materiálu: identifikace kolicinů a mikrocinů v souborech komensálních a patogenních kmenů

Přiložené soubory

1950.full.pdf

Vyhledat podobné dokumenty

Citovat

BOSÁK, Juraj, Petra LAIBLOVA, Jan ŠMARDA, Daniela DĚDIČOVÁ a David ŠMAJS. Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation. Journal of Bacteriology. WASHINGTON: AMER SOC MICROBIOLOGY, 2012, roč. 194, č. 8, s. 1950-1959. ISSN 0021-9193. Dostupné z: https://dx.doi.org/10.1128/JB.05885-11.

@article{1075188,
   author = {Bosák, Juraj and Laiblova, Petra and Šmarda, Jan and Dědičová, Daniela and Šmajs, David},
   article_location = {WASHINGTON},
   article_number = {8},
   doi = {http://dx.doi.org/10.1128/JB.05885-11},
   keywords = {HUMAN ESCHERICHIA-COLI; SON-KILLER BACTERIUM; SP-NOV; OUTER-MEMBRANE; ARSENOPHONUS-NASONIAE; SERRATIA-MARCESCENS; NUCLEOTIDE-SEQUENCE; VIRULENCE FACTOR; GENOME SEQUENCE; PESTICIN},
   language = {eng},
   issn = {0021-9193},
   journal = {Journal of Bacteriology},
   title = {Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation},
   volume = {194},
   year = {2012}
}

TY  - JOUR
ID  - 1075188
AU  - Bosák, Juraj - Laiblova, Petra - Šmarda, Jan - Dědičová, Daniela - Šmajs, David
PY  - 2012
TI  - Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation
JF  - Journal of Bacteriology
VL  - 194
IS  - 8
SP  - 1950-1959
EP  - 1950-1959
PB  - AMER SOC MICROBIOLOGY
SN  - 00219193
KW  - HUMAN ESCHERICHIA-COLI
KW  - SON-KILLER BACTERIUM
KW  - SP-NOV
KW  - OUTER-MEMBRANE
KW  - ARSENOPHONUS-NASONIAE
KW  - SERRATIA-MARCESCENS
KW  - NUCLEOTIDE-SEQUENCE
KW  - VIRULENCE FACTOR
KW  - GENOME SEQUENCE
KW  - PESTICIN
N2  - A novel colicin type, designated colicin F-Y, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F-Y was active against both pathogenic and nonpathogenic strains of the genus Yersinia. Plasmid YF27601 (5,574 bp) of Y. frederiksenii Y27601 was completely sequenced. The colicin F-Y activity gene (cfyA) and the colicin F-Y immunity gene (cfyI) were identified. The deduced amino acid sequence of colicin F-Y was very similar in its C-terminal pore-forming domain to colicin Ib (69% identity in the last 178 amino acid residues), indicating pore forming as its lethal mode of action. Transposon mutagenesis of the colicin F-Y-susceptible strain Yersinia kristensenii Y276 revealed the yiuR gene (ykris001_4440), which encodes the YiuR outer membrane protein with unknown function, as the colicin F-Y receptor molecule. Introduction of the yiuR gene into the colicin F-Y-resistant strain Y. kristensenii Y104 restored its susceptibility to colicin F-Y. In contrast, the colicin F-Y-resistant strain Escherichia coli TOP10F' acquired susceptibility to colicin F-Y only when both the yiuR and tonB genes from Y. kristensenii Y276 were introduced. Similarities between colicins F-Y and Ib, similarities between the Cir and YiuR receptors, and the detected partial cross-immunity of colicin F-Y and colicin Ib producers suggest a common evolutionary origin of the colicin F-Y-YiuR and colicin Ib-Cir systems.
ER  -

BOSÁK, Juraj, Petra LAIBLOVA, Jan ŠMARDA, Daniela DĚDIČOVÁ a David ŠMAJS. Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation. \textit{Journal of Bacteriology}. WASHINGTON: AMER SOC MICROBIOLOGY, 2012, roč.~194, č.~8, s.~1950-1959. ISSN~0021-9193. Dostupné z: https://dx.doi.org/10.1128/JB.05885-11.

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