Comparison of outcomes in ST-segment depression and ST-segment
elevation myocardial infarction patients treated with emergency
PCI: Data from a multicentre registry

J 2012

Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry

KNOT, J.; Petr KALA; Richard ROKYTA; J. STASEK; B. KUZMANOV et. al.

Basic information

Original name

Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry

Authors

KNOT, J. (203 Czech Republic, guarantor); Petr KALA (203 Czech Republic, belonging to the institution); Richard ROKYTA (203 Czech Republic); J. STASEK (203 Czech Republic); B. KUZMANOV (100 Bulgaria); Ota HLINOMAZ (203 Czech Republic, belonging to the institution); J. BĔLOHLAVEK (203 Czech Republic); F. ROHAC (203 Czech Republic); R. PETR (203 Czech Republic); D. BILKOVA (203 Czech Republic); S. DJAMBAZOV (203 Czech Republic); M. GRIGOROV (100 Bulgaria) and P. WIDIMSKY (203 Czech Republic)

Edition

Cardiovascular Journal of Africa, 2012, 1995-1892

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

South Africa

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 0.848

RIV identification code

RIV/00216224:14110/12:00062228

Organization unit

Faculty of Medicine

UT WoS

000311351300009

Keywords in English

Acute myocardial infarction; Coronary artery disease; Primary PCI

Abstract

In the original language

Traditionally, acute myocardial infarction (AMI) has been described as either STEMI (ST-elevation myocardial infarction) or non-STEMI myocardial infarction. This classification is historically related to the use of thrombolytic therapy, which is effective in STEMI. The current era of widespread use of coronary angiography (CAG), usually followed by primary percutaneous coronary intervention (PCI) puts this classification system into question. Objectives: To compare the outcomes of patients with STEMI and ST-depression myocardial infarction (STDMI) who were treated with emergency PCI. Methods: This multicentre registry enrolled a total of 6 602 consecutive patients with AMI. Patients were divided into the following subgroups: STEMI (n = 3446), STDMI (n = 907), left bundle branch block (LBBB) AMI (n = 241), right bundle branch block (RBBB) AMI (n = 338) and other electrocardiographic (ECG) AMI (n = 1670). Baseline and angiographic characteristics were studied, and revascularisation therapies and in-hospital mortality were analysed. Results: Acute heart failure was present in 29.5% of the STDMI vs 27.4% of the STEMI patients (p < 0.001). STDMI patients had more extensive coronary atherosclerosis than patients with STEMI (three-vessel disease: 53.1 vs 30%). The left main coronary artery was an infract-related artery (IRA) in 6.0% of STDMI vs 1.1% of STEMI patients. TIMI flow 0-1 was found in 35.0% of STDMI vs 66.0% of STEMI patients. Primary PCI was performed in 88.1% of STEMI (with a success rate of 90.8%) vs 61.8% of STDMI patients (with a success rate of 94.5%) (p = 0.012 for PCI success rates). In-hospital mortality was not significantly different (STDMI 6.3 vs STEMI 5.4%, p = 0.330). Conclusion: These data suggest that similar strategies (emergency CAG with PCI whenever feasible) should be applied to both these types of AMI.

Cite

KNOT, J.; Petr KALA; Richard ROKYTA; J. STASEK; B. KUZMANOV; Ota HLINOMAZ; J. BĔLOHLAVEK; F. ROHAC; R. PETR; D. BILKOVA; S. DJAMBAZOV; M. GRIGOROV and P. WIDIMSKY. Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry. Cardiovascular Journal of Africa. 2012, vol. 23, No 9, p. 495-500. ISSN 1995-1892.

@article{1076475,
   author = {Knot, J. and Kala, Petr and Rokyta, Richard and Stasek, J. and Kuzmanov, B. and Hlinomaz, Ota and Bĕlohlavek, J. and Rohac, F. and Petr, R. and Bilkova, D. and Djambazov, S. and Grigorov, M. and Widimsky, P.},
   article_number = {9},
   keywords = {Acute myocardial infarction; Coronary artery disease; Primary PCI},
   language = {eng},
   issn = {1995-1892},
   journal = {Cardiovascular Journal of Africa},
   title = {Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry},
   volume = {23},
   year = {2012}
}

TY  - JOUR
ID  - 1076475
AU  - Knot, J. - Kala, Petr - Rokyta, Richard - Stasek, J. - Kuzmanov, B. - Hlinomaz, Ota - Bĕlohlavek, J. - Rohac, F. - Petr, R. - Bilkova, D. - Djambazov, S. - Grigorov, M. - Widimsky, P.
PY  - 2012
TI  - Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry
JF  - Cardiovascular Journal of Africa
VL  - 23
IS  - 9
SP  - 495-500
EP  - 495-500
SN  - 19951892
KW  - Acute myocardial infarction
KW  - Coronary artery disease
KW  - Primary PCI
N2  - Traditionally, acute myocardial infarction (AMI) has been described as either STEMI (ST-elevation myocardial infarction) or non-STEMI myocardial infarction. This classification is historically related to the use of thrombolytic therapy, which is effective in STEMI. The current era of widespread use of coronary angiography (CAG), usually followed by primary percutaneous coronary intervention (PCI) puts this classification system into question. Objectives: To compare the outcomes of patients with STEMI and ST-depression myocardial infarction (STDMI) who were treated with emergency PCI. Methods: This multicentre registry enrolled a total of 6 602 consecutive patients with AMI. Patients were divided into the following subgroups: STEMI (n = 3446), STDMI (n = 907), left bundle branch block (LBBB) AMI (n = 241), right bundle branch block (RBBB) AMI (n = 338) and other electrocardiographic (ECG) AMI (n = 1670). Baseline and angiographic characteristics were studied, and revascularisation therapies and in-hospital mortality were analysed. Results: Acute heart failure was present in 29.5% of the STDMI vs 27.4% of the STEMI patients (p < 0.001). STDMI patients had more extensive coronary atherosclerosis than patients with STEMI (three-vessel disease: 53.1 vs 30%). The left main coronary artery was an infract-related artery (IRA) in 6.0% of STDMI vs 1.1% of STEMI patients. TIMI flow 0-1 was found in 35.0% of STDMI vs 66.0% of STEMI patients. Primary PCI was performed in 88.1% of STEMI (with a success rate of 90.8%) vs 61.8% of STDMI patients (with a success rate of 94.5%) (p = 0.012 for PCI success rates). In-hospital mortality was not significantly different (STDMI 6.3 vs STEMI 5.4%, p = 0.330). Conclusion: These data suggest that similar strategies (emergency CAG with PCI whenever feasible) should be applied to both these types of AMI.
ER  -

KNOT, J.; Petr KALA; Richard ROKYTA; J. STASEK; B. KUZMANOV; Ota HLINOMAZ; J. BĔLOHLAVEK; F. ROHAC; R. PETR; D. BILKOVA; S. DJAMBAZOV; M. GRIGOROV and P. WIDIMSKY. Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI: Data from a multicentre registry. \textit{Cardiovascular Journal of Africa}. 2012, vol.~23, No~9, p.~495-500. ISSN~1995-1892.

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