TOMANDLOVÁ, Marie, Josef TOMANDL, Jaroslav MELUZÍN, Jiří PAŘENICA, Eva TÁBORSKÁ and Jindřich ŠPINAR. Determination of soluble ST2 by MAP technology. In Planet xMAP 2012. 2012.
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Basic information
Original name Determination of soluble ST2 by MAP technology
Authors TOMANDLOVÁ, Marie, Josef TOMANDL, Jaroslav MELUZÍN, Jiří PAŘENICA, Eva TÁBORSKÁ and Jindřich ŠPINAR.
Edition Planet xMAP 2012, 2012.
Other information
Type of outcome Conference abstract
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English ST2; heart failure; MAP technology
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 4/11/2013 10:57.
Abstract
Production sST2 in cardiomyocytes and fibroblasts is stimulated by myocardial mechanical stress. sST2 is considered a decoy receptor of IL-33 that blocks the protective effect of the cytokine in atherosclerosis and myocardial remodelling. Concentration of sST2 was measured using on the Luminex. We found that in patients with chronic heart failure sST2 values were not significantly elevated.In patients with cardiogenic shock was observed a 50% decrease of sST2 plasma concentration within 96 hours.Current data suggest that sST2 monitoring has primarily prognostic significance.
Links
MUNI/A/0831/2011, interní kód MUName: Příspěvek chemických a biochemických metodik ke studiu molekulární podstaty vybraných patologických stavů a onemocnění
Investor: Masaryk University, Category A
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