Comparison of parturient – controlled remifentanil with
epidural bupivacain  and sufentanil for labour analgesia:
Randomised controlled trial

J 2014

Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA et. al.

Základní údaje

Originální název

Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial

Název česky

Srovnání rodičkou řízeného podání remifentanilu s epidurální analgezií bupivakainem a sufentanilem u porodu: randomizovaná studie

Autoři

ŠTOURAČ, Petr (203 Česká republika, garant, domácí), Hana HARAZIM (203 Česká republika, domácí), Marta STODŮLKOVÁ (203 Česká republika, domácí), Martin HUSER (203 Česká republika, domácí), Ivo KŘIKAVA (203 Česká republika, domácí), Petr JANKŮ (203 Česká republika, domácí), Olga HAKLOVA (203 Česká republika), Lubomír HAKL (203 Česká republika, domácí), Roman ŠTOUDEK (203 Česká republika, domácí), Roman GÁL (203 Česká republika, domácí) a Pavel ŠEVČÍK (203 Česká republika, domácí)

Vydání

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic, Olomouc, Palacký University, 2014, 1213-8118

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.200

Kód RIV

RIV/00216224:14110/14:00074648

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.5507/bp.2012.073

UT WoS

000338628200011

Klíčová slova česky

porodní analgezie; epidurální analgezie; rodičkou řízená intravenózní analgezie; remifentanil

Klíčová slova anglicky

obstetric analgesia; epidural analgesia; parturient-controlled intravenous analgesia; remifentanil

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 4. 2015 13:19, Ing. Mgr. Věra Pospíšilíková

Anotace

V originále

Epidural analgesia (EA) has significant contraindications including coagulation disorders and parturient refusal. One alternative is intravenous self-administered analgesia using the ultra short-acting opioid remifentanil (rPCA). We compared the efficiency and safety of standard epidural analgesia with parturient-controlled intravenous analgesia using remifentanil as well as personal satisfaction. We enrolled twelve ASA I classified women with singleton pregnancy who delivered vaginally in the period 3/2010-5/2010 and who received rPCA (n=12) in standard analgesic protocol: 20 mcg boluses using PCA pump with a lockout interval of 3 min. The control group consisted of 12 pregnant women who received EA (n=12): 0.125% bupivacaine with sufentanil 0.5 mcg/mL in top-up boluses every hour until delivery. Data were acquired from standard Acute Pain Service (APS) form and patient medical records (demographic, labour course parameters), Visual Analogue Scale (VAS), Bromage Scale (BS) and adverse effects of analgesia. There were no demographic or labour course parameter differences between groups (P>0.05). The differences in VAS decrease (P=0.056) and parturient satisfaction (P=0.24) during the whole analgesia administration were statistically insignificant. The main limitation of the study was small sample and enrolment of healthy singleton pregnant women only. Remifentanil use in obstetric analgesia is a viable alternative to EA, especially in cases of EA contraindications and parturient disapproval.

Přiložené soubory

Comparison_of_parturient.pdf

Požádat o autorskou verzi souboru

Citovat

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA, Petr JANKŮ, Olga HAKLOVA, Lubomír HAKL, Roman ŠTOUDEK, Roman GÁL a Pavel ŠEVČÍK. Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial. Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic. Olomouc: Palacký University, 2014, roč. 158, č. 2, s. 227-232. ISSN 1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2012.073.

@article{1081519,
   author = {Štourač, Petr and Harazim, Hana and Stodůlková, Marta and Huser, Martin and Křikava, Ivo and Janků, Petr and Haklova, Olga and Hakl, Lubomír and Štoudek, Roman and Gál, Roman and Ševčík, Pavel},
   article_location = {Olomouc},
   article_number = {2},
   doi = {http://dx.doi.org/10.5507/bp.2012.073},
   keywords = {obstetric analgesia; epidural analgesia; parturient-controlled intravenous analgesia; remifentanil},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic},
   title = {Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial},
   url = {http://biomed.papers.upol.cz/pdfs/bio/2014/02/11.pdf},
   volume = {158},
   year = {2014}
}

TY  - JOUR
ID  - 1081519
AU  - Štourač, Petr - Harazim, Hana - Stodůlková, Marta - Huser, Martin - Křikava, Ivo - Janků, Petr - Haklova, Olga - Hakl, Lubomír - Štoudek, Roman - Gál, Roman - Ševčík, Pavel
PY  - 2014
TI  - Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial
JF  - Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic
VL  - 158
IS  - 2
SP  - 227-232
EP  - 227-232
PB  - Palacký University
SN  - 12138118
KW  - obstetric analgesia
KW  - epidural analgesia
KW  - parturient-controlled intravenous analgesia
KW  - remifentanil
UR  - http://biomed.papers.upol.cz/pdfs/bio/2014/02/11.pdf
N2  - Epidural analgesia (EA) has significant contraindications including coagulation disorders and parturient refusal. One alternative is intravenous self-administered analgesia using the ultra short-acting opioid remifentanil (rPCA). We compared the efficiency and safety of standard epidural analgesia with parturient-controlled intravenous analgesia using remifentanil as well as personal satisfaction. We enrolled twelve ASA I classified women with singleton pregnancy who delivered vaginally in the period 3/2010-5/2010 and who received rPCA (n=12) in standard analgesic protocol: 20 mcg boluses using PCA pump with a lockout interval of 3 min. The control group consisted of 12 pregnant women who received EA (n=12): 0.125% bupivacaine with sufentanil 0.5 mcg/mL in top-up boluses every hour until delivery. Data were acquired from standard Acute Pain Service (APS) form and patient medical records (demographic, labour course parameters), Visual Analogue Scale (VAS), Bromage Scale (BS) and adverse effects of analgesia. There were no demographic or labour course parameter differences between groups (P>0.05). The differences in VAS decrease (P=0.056) and parturient satisfaction (P=0.24) during the whole analgesia administration were statistically insignificant. The main limitation of the study was small sample and enrolment of healthy singleton pregnant women only. Remifentanil use in obstetric analgesia is a viable alternative to EA, especially in cases of EA contraindications and parturient disapproval.
ER  -

ŠTOURAČ, Petr, Hana HARAZIM, Marta STODŮLKOVÁ, Martin HUSER, Ivo KŘIKAVA, Petr JANKŮ, Olga HAKLOVA, Lubomír HAKL, Roman ŠTOUDEK, Roman GÁL a Pavel ŠEVČÍK. Comparison of parturient – controlled remifentanil with epidural bupivacain and sufentanil for labour analgesia: Randomised controlled trial. \textit{Biomedical papers of the Medical Faculty of the University Palacký, Olomouc Czech Republic}. Olomouc: Palacký University, 2014, roč.~158, č.~2, s.~227-232. ISSN~1213-8118. Dostupné z: https://dx.doi.org/10.5507/bp.2012.073.

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