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@inproceedings{1085603,
author = {Jurák, Pavel and Zvoníček, Václav and Leinveber, Pavel and Halámek, Josef and Vondra, Vlastimil},
address = {Neuveden},
booktitle = {34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
doi = {http://dx.doi.org/10.1109/EMBC.2012.6346800},
editor = {Lovell Nigel},
keywords = {Baroreflex; Blood pressure; Heart rate variability; Resonant frequency; TV; Ventilation},
howpublished = {elektronická verze "online"},
language = {eng},
location = {Neuveden},
isbn = {978-1-4244-4119-8},
pages = {3821-3824},
publisher = {Neuveden},
title = {Respiratory induced heart rate and blood pressure variability during mechanical ventilation in critically ill and brain death patients},
year = {2012}
}
TY - JOUR
ID - 1085603
AU - Jurák, Pavel - Zvoníček, Václav - Leinveber, Pavel - Halámek, Josef - Vondra, Vlastimil
PY - 2012
TI - Respiratory induced heart rate and blood pressure variability during mechanical ventilation in critically ill and brain death patients
PB - Neuveden
CY - Neuveden
SN - 9781424441198
KW - Baroreflex
KW - Blood pressure
KW - Heart rate variability
KW - Resonant frequency
KW - TV
KW - Ventilation
N2 - We analysed respiratory induced heart rate and blood pressure variability in mechanically ventilated patients with different levels of sedation and central nervous system activity. Our aim was to determine whether it is possible to distinguish different levels of sedation or human brain activity from heart rate and blood pressure. We measured 19 critically ill and 15 brain death patients ventilated at various respiratory frequencies - 15, 12, 8 and 6 breaths per minute. Basal and deeper sedation was performed in the critically ill patients. We detected and analysed heart rate and blood pressure parameters induced by ventilation. Results: Respiratory induced heart rate variability is the unique parameter that can differentiate between brain death patients and sedated critically ill patients. Significant differences exist, especially during slow deep breathing with a mean period of 10 seconds. The limit values reflecting brain death are: baroreflex lower than 0.5 ms/mmHg and tidal volume normalised heart rate variability lower than 0.5 ms/ml. Reduced heart rate variability parameters of brain death patients remain unchanged even after normalisation to respiration volume. However, differences between basal and deep sedation do not appear significant on any parameter.
ER -
JURÁK, Pavel, Václav ZVONÍČEK, Pavel LEINVEBER, Josef HALÁMEK a Vlastimil VONDRA. Respiratory induced heart rate and blood pressure variability during mechanical ventilation in critically ill and brain death patients. Online. In Lovell Nigel. \textit{34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society}. Neuveden: Neuveden, 2012, s.~3821-3824. ISBN~978-1-4244-4119-8. Dostupné z: https://dx.doi.org/10.1109/EMBC.2012.6346800.
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