| BUCHLOVIČ, Marian, Zdeněk KŘÍŽ, Ctirad HOFR and Milan POTÁČEK. New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA. Bioorganic & Medicinal Chemistry. Elsevier, 2013, vol. 21, No 5, p. 1078-1081. ISSN 0968-0896. Available from: https://dx.doi.org/10.1016/j.bmc.2013.01.004. |
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@article{1086562,
author = {Buchlovič, Marian and Kříž, Zdeněk and Hofr, Ctirad and Potáček, Milan},
article_number = {5},
doi = {http://dx.doi.org/10.1016/j.bmc.2013.01.004},
keywords = {Polycyclic aromatic hydrocarbon (PAH);Nitrones;DNA;Intercalation;Docking},
language = {eng},
issn = {0968-0896},
journal = {Bioorganic & Medicinal Chemistry},
title = {New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA},
url = {http://www.sciencedirect.com/science/article/pii/S096808961300031X},
volume = {21},
year = {2013}
}
TY - JOUR
ID - 1086562
AU - Buchlovič, Marian - Kříž, Zdeněk - Hofr, Ctirad - Potáček, Milan
PY - 2013
TI - New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA
JF - Bioorganic & Medicinal Chemistry
VL - 21
IS - 5
SP - 1078-1081
EP - 1078-1081
PB - Elsevier
SN - 09680896
KW - Polycyclic aromatic hydrocarbon (PAH);Nitrones;DNA;Intercalation;Docking
UR - http://www.sciencedirect.com/science/article/pii/S096808961300031X
N2 - Novel approach to functionalized polycyclic aromatic hydrocarbons (PAHs) is presented. Incorporation of cyclic nitrone framework into the structure of PAHs was studied with respect to their anti-proliferative activities and interaction with double stranded DNA. Theoretical docking studies and UV titration methods were used for preliminary evaluation of binding of new PAH derivatives to DNA structure.
ER -
BUCHLOVIČ, Marian, Zdeněk KŘÍŽ, Ctirad HOFR and Milan POTÁČEK. New PAH derivatives functionalized by cyclic nitrone framework: Synthetic design, anti-proliferative activity and interaction with DNA. \textit{Bioorganic \&{} Medicinal Chemistry}. Elsevier, 2013, vol.~21, No~5, p.~1078-1081. ISSN~0968-0896. Available from: https://dx.doi.org/10.1016/j.bmc.2013.01.004.
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