| RYZÍ, Michal, Milan BRÁZDIL, Zdeněk NOVÁK, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Ivan REKTOR a Robert KUBA. Long-term vagus nerve stimulation in children with focal epilepsy. ACTA NEUROLOGICA SCANDINAVICA. MALDEN, USA: WILEY-BLACKWELL, 2013, roč. 127, č. 5, s. 316-322. ISSN 0001-6314. Dostupné z: https://dx.doi.org/10.1111/ane.12009. |
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@article{1087789,
author = {Ryzí, Michal and Brázdil, Milan and Novák, Zdeněk and Chrastina, Jan and Ošlejšková, Hana and Rektor, Ivan and Kuba, Robert},
article_location = {MALDEN, USA},
article_number = {5},
doi = {http://dx.doi.org/10.1111/ane.12009},
keywords = {child neurology; epilepsy; quality of life; seizures; treatment},
language = {eng},
issn = {0001-6314},
journal = {ACTA NEUROLOGICA SCANDINAVICA},
title = {Long-term vagus nerve stimulation in children with focal epilepsy},
volume = {127},
year = {2013}
}
TY - JOUR
ID - 1087789
AU - Ryzí, Michal - Brázdil, Milan - Novák, Zdeněk - Chrastina, Jan - Ošlejšková, Hana - Rektor, Ivan - Kuba, Robert
PY - 2013
TI - Long-term vagus nerve stimulation in children with focal epilepsy
JF - ACTA NEUROLOGICA SCANDINAVICA
VL - 127
IS - 5
SP - 316-322
EP - 316-322
PB - WILEY-BLACKWELL
SN - 00016314
KW - child neurology
KW - epilepsy
KW - quality of life
KW - seizures
KW - treatment
N2 - Objectives – The aim of the study was to evaluate the long-term efficacy and hospitalization rates in children with refractory focal epilepsy treated by vagus nerve stimulation. Materials and methods – We retrospectively analyzed 15 children with intractable focal epilepsy treated by vagus nerve stimulation (mean age of 14.6 +/- 2.5 years at the time of implantation). We analyzed the treatment effectiveness at 1, 2, and 5 year follow-up visits. We counted the average number of urgent hospitalizations and number of days of urgent hospitalization per year for each patient before and after the VNS implantation. Results – The mean seizure reduction was 42.5% at 1 year, 54.9% at 2 years, and 58.3% at 5 years. The number of responders was 7 (46.7%) at 1 year and 9 (60%) at both 2 and 5 years. The mean number of urgent hospitalizations per patient was 1.0 +/- 0.6 per year preoperatively and 0.3 +/- 0.5 per year post-operatively. The mean number of days of urgent hospitalization per patient was 9.3 +/- 6.1 per year preoperatively and 1.3 +/- 1.8 per year postoperatively. Conclusions – Vagus nerve stimulation is an effective method of treating children with refractory focal epilepsy. It leads to a substantial decrease in the number and duration of urgent hospitalizations.
ER -
RYZÍ, Michal, Milan BRÁZDIL, Zdeněk NOVÁK, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Ivan REKTOR a Robert KUBA. Long-term vagus nerve stimulation in children with focal epilepsy. \textit{ACTA NEUROLOGICA SCANDINAVICA}. MALDEN, USA: WILEY-BLACKWELL, 2013, roč.~127, č.~5, s.~316-322. ISSN~0001-6314. Dostupné z: https://dx.doi.org/10.1111/ane.12009.
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