Long-term survival following acute heart failure: The Acute
Heart Failure Database Main registry (AHEAD Main)

J 2013

Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main)

PAŘENICA, Jiří; Jindřich ŠPINAR; Jiří VÍTOVEC; Petr WIDIMSKY; Ales LINHART et al.

Základní údaje

Originální název

Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main)

Autoři

Vydání

European Journal of Internal Medicine, AMSTERDAM, ELSEVIER SCIENCE BV, 2013, 0953-6205

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.300

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14110/13:00067905

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1016/j.ejim.2012.11.005

UT WoS

000314786000018

Klíčová slova anglicky

Acute heart failure; AHEAD; Prognosis

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 4. 2. 2014 16:20, Soňa Böhmová

Anotace

V originále

Background: The in-hospital mortality of patients with acute heart failure (AHF) is reported to be 12.7% and mortality on day 30 after admission 17.2%. Less information is known about the long-term prognosis of those patients discharged after hospitalization. As such, the aim of this study was to investigate long-term survival in a cohort of patients who had been hospitalized for AHF and then discharged. Methods: The AHEAD Main registry includes 4153 patients hospitalized for AHF in 7 different medical centers, each with its own cathlab, in the Czech Republic. Patient survival rates were evaluated in 3438 patients who had survived to day 30 after admission, and were used as a measurement of long-term survival. Results: The most common etiologies were acute coronary syndrome (32.3%) and chronic ischemic heart disease (20.1%). The survival rate after day 30 following admission was 79.7% after 1 year and 64.5% after 3 years. No statistically significant difference in syndromes was found in survival after day 30. Independent predictors of a worse prognosis were defined as follows: age > 70 years, comorbidities, severe left ventricular systolic dysfunction, valvular disease or ACS as an etiology of AHF. A better prognosis was defined for de-novo AHF patients, and those who were taking ACE inhibitors at the time of discharge. In a sub-analysis, high levels of natriuretic peptides were the most powerful predictors of high-risk, long-term mortality. Conclusion: The AHEAD Main registry provides up-to-date information on the long-term prognosis of patients hospitalized with AHF. The 3-year survival of patients following day 30 of admission was 64.5%. Higher age, LV dysfunction, comorbidities and high levels of natriuretic peptides were the most powerful predictors of worse prognosis in long-term survival.

Přiložené soubory

parenica_EurJIntMed.pdf

Požádat o autorskou verzi souboru

Citovat

PAŘENICA, Jiří; Jindřich ŠPINAR; Jiří VÍTOVEC; Petr WIDIMSKY; Ales LINHART; Marian FEDORCO; Jan VACLAVIK; Roman MIKLÍK; Marián FELŠŐCI; Kateřina HOŘÁKOVÁ; Cestmir CIHALIK; Filip MALEK; Lenka ŠPINAROVÁ; Jan BĚLOHLÁVEK; Jiří KETTNER; Kamil ZEMAN; Ladislav DUŠEK a Jiří JARKOVSKÝ. Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main). European Journal of Internal Medicine. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč. 24, č. 2, s. 151-160. ISSN 0953-6205. Dostupné z: https://doi.org/10.1016/j.ejim.2012.11.005.

@article{1091435,
   author = {Pařenica, Jiří and Špinar, Jindřich and Vítovec, Jiří and Widimsky, Petr and Linhart, Ales and Fedorco, Marian and Vaclavik, Jan and Miklík, Roman and Felšőci, Marián and Hořáková, Kateřina and Cihalik, Cestmir and Malek, Filip and Špinarová, Lenka and Bělohlávek, Jan and Kettner, Jiří and Zeman, Kamil and Dušek, Ladislav and Jarkovský, Jiří},
   article_location = {AMSTERDAM},
   article_number = {2},
   doi = {https://doi.org/10.1016/j.ejim.2012.11.005},
   keywords = {Acute heart failure; AHEAD; Prognosis},
   language = {eng},
   issn = {0953-6205},
   journal = {European Journal of Internal Medicine},
   title = {Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main)},
   volume = {24},
   year = {2013}
}

TY  - JOUR
ID  - 1091435
AU  - Pařenica, Jiří - Špinar, Jindřich - Vítovec, Jiří - Widimsky, Petr - Linhart, Ales - Fedorco, Marian - Vaclavik, Jan - Miklík, Roman - Felšőci, Marián - Hořáková, Kateřina - Cihalik, Cestmir - Malek, Filip - Špinarová, Lenka - Bělohlávek, Jan - Kettner, Jiří - Zeman, Kamil - Dušek, Ladislav - Jarkovský, Jiří
PY  - 2013
TI  - Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main)
JF  - European Journal of Internal Medicine
VL  - 24
IS  - 2
SP  - 151-160
EP  - 151-160
PB  - ELSEVIER SCIENCE BV
SN  - 09536205
KW  - Acute heart failure
KW  - AHEAD
KW  - Prognosis
N2  - Background: The in-hospital mortality of patients with acute heart failure (AHF) is reported to be 12.7% and mortality on day 30 after admission 17.2%. Less information is known about the long-term prognosis of those patients discharged after hospitalization. As such, the aim of this study was to investigate long-term survival in a cohort of patients who had been hospitalized for AHF and then discharged. Methods: The AHEAD Main registry includes 4153 patients hospitalized for AHF in 7 different medical centers, each with its own cathlab, in the Czech Republic. Patient survival rates were evaluated in 3438 patients who had survived to day 30 after admission, and were used as a measurement of long-term survival. Results: The most common etiologies were acute coronary syndrome (32.3%) and chronic ischemic heart disease (20.1%). The survival rate after day 30 following admission was 79.7% after 1 year and 64.5% after 3 years. No statistically significant difference in syndromes was found in survival after day 30. Independent predictors of a worse prognosis were defined as follows: age > 70 years, comorbidities, severe left ventricular systolic dysfunction, valvular disease or ACS as an etiology of AHF. A better prognosis was defined for de-novo AHF patients, and those who were taking ACE inhibitors at the time of discharge. In a sub-analysis, high levels of natriuretic peptides were the most powerful predictors of high-risk, long-term mortality. Conclusion: The AHEAD Main registry provides up-to-date information on the long-term prognosis of patients hospitalized with AHF. The 3-year survival of patients following day 30 of admission was 64.5%. Higher age, LV dysfunction, comorbidities and high levels of natriuretic peptides were the most powerful predictors of worse prognosis in long-term survival.
ER  -

PAŘENICA, Jiří; Jindřich ŠPINAR; Jiří VÍTOVEC; Petr WIDIMSKY; Ales LINHART; Marian FEDORCO; Jan VACLAVIK; Roman MIKLÍK; Marián FELŠ$\backslash$H OCI; Kateřina HOŘÁKOVÁ; Cestmir CIHALIK; Filip MALEK; Lenka ŠPINAROVÁ; Jan BĚLOHLÁVEK; Jiří KETTNER; Kamil ZEMAN; Ladislav DUŠEK a Jiří JARKOVSKÝ. Long-term survival following acute heart failure: The Acute Heart Failure Database Main registry (AHEAD Main). \textit{European Journal of Internal Medicine}. AMSTERDAM: ELSEVIER SCIENCE BV, 2013, roč.~24, č.~2, s.~151-160. ISSN~0953-6205. Dostupné z: https://doi.org/10.1016/j.ejim.2012.11.005.

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