Default Mode Network and Extrastriate Visual Resting State
Network in Patients with Parkinson's Disease Dementia

J 2012

Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL

Základní údaje

Originální název

Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia

Autoři

REKTOROVÁ, Irena (203 Česká republika, garant, domácí), Lenka KRAJČOVIČOVÁ (703 Slovensko, domácí), Radek MAREČEK (203 Česká republika, domácí) a Michal MIKL (203 Česká republika, domácí)

Vydání

Neurodegenerative Diseases, Basel, Switzerland, Karger, 2012, 1660-2854

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.410

Kód RIV

RIV/00216224:14740/12:00064605

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1159/000334765

UT WoS

000303660600049

Klíčová slova anglicky

Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 4. 2013 08:51, Olga Křížová

Anotace

V originále

Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel

Návaznosti

MSM0021622404, záměr

Název: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS

Citovat

REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. Neurodegenerative Diseases. Basel, Switzerland: Karger, 2012, roč. 10, 1-4, s. 232-237. ISSN 1660-2854. Dostupné z: https://dx.doi.org/10.1159/000334765.

@article{1094319,
   author = {Rektorová, Irena and Krajčovičová, Lenka and Mareček, Radek and Mikl, Michal},
   article_location = {Basel, Switzerland},
   article_number = {1-4},
   doi = {http://dx.doi.org/10.1159/000334765},
   keywords = {Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity},
   language = {eng},
   issn = {1660-2854},
   journal = {Neurodegenerative Diseases},
   title = {Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia},
   url = {http://www.karger.com/Article/Abstract/334765},
   volume = {10},
   year = {2012}
}

TY  - JOUR
ID  - 1094319
AU  - Rektorová, Irena - Krajčovičová, Lenka - Mareček, Radek - Mikl, Michal
PY  - 2012
TI  - Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia
JF  - Neurodegenerative Diseases
VL  - 10
IS  - 1-4
SP  - 232-237
EP  - 232-237
PB  - Karger
SN  - 16602854
KW  - Default mode network
KW  - Extrastriate visual resting state network
KW  - Parkinson's disease dementia
KW  - Functional connectivity
UR  - http://www.karger.com/Article/Abstract/334765
L2  - http://www.karger.com/Article/Abstract/334765
N2  - Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel
ER  -

REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. \textit{Neurodegenerative Diseases}. Basel, Switzerland: Karger, 2012, roč.~10, 1-4, s.~232-237. ISSN~1660-2854. Dostupné z: https://dx.doi.org/10.1159/000334765.

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