REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. Neurodegenerative Diseases. Basel, Switzerland: Karger, 2012, roč. 10, 1-4, s. 232-237. ISSN 1660-2854. Dostupné z: https://dx.doi.org/10.1159/000334765. |
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@article{1094319, author = {Rektorová, Irena and Krajčovičová, Lenka and Mareček, Radek and Mikl, Michal}, article_location = {Basel, Switzerland}, article_number = {1-4}, doi = {http://dx.doi.org/10.1159/000334765}, keywords = {Default mode network; Extrastriate visual resting state network; Parkinson's disease dementia; Functional connectivity}, language = {eng}, issn = {1660-2854}, journal = {Neurodegenerative Diseases}, title = {Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia}, url = {http://www.karger.com/Article/Abstract/334765}, volume = {10}, year = {2012} }
TY - JOUR ID - 1094319 AU - Rektorová, Irena - Krajčovičová, Lenka - Mareček, Radek - Mikl, Michal PY - 2012 TI - Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia JF - Neurodegenerative Diseases VL - 10 IS - 1-4 SP - 232-237 EP - 232-237 PB - Karger SN - 16602854 KW - Default mode network KW - Extrastriate visual resting state network KW - Parkinson's disease dementia KW - Functional connectivity UR - http://www.karger.com/Article/Abstract/334765 L2 - http://www.karger.com/Article/Abstract/334765 N2 - Aims: Using fMRI, we evaluated the default mode network (DMN) and the extrastriate visual resting state network (ESV-RSN) in 14 patients with Parkinson's disease dementia (PDD) as compared with 18 patients with Parkinson's disease (PD) without dementia and 18 healthy controls (HC). Methods: We analyzed the seed-based functional connectivity of both resting state data and deactivations during a visual complex scene-encoding task. Results: Using the posterior cingulate cortex/precuneus as a seed for the DMN analysis, we observed significant decreases of connectivity in the right inferior frontal gyrus in PDD as compared to PD and HC. Using the caudate nucleus as a seed for the ESV-RSN analysis, we found significant decreases of connectivity in the left and right inferior occipital gyrus in PDD as compared to HC. Conclusion: Differences in functional connectivity patterns between PDD and PD/HC were observed in areas known to be engaged in stimulus-driven reorienting of attention and in visual processing. Copyright (C) 2012 S. Karger AG, Basel ER -
REKTOROVÁ, Irena, Lenka KRAJČOVIČOVÁ, Radek MAREČEK a Michal MIKL. Default Mode Network and Extrastriate Visual Resting State Network in Patients with Parkinson's Disease Dementia. \textit{Neurodegenerative Diseases}. Basel, Switzerland: Karger, 2012, roč.~10, 1-4, s.~232-237. ISSN~1660-2854. Dostupné z: https://dx.doi.org/10.1159/000334765.
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