BIENERTOVÁ VAŠKŮ, Julie, Jiří ŠÁNA and Ondřej SLABÝ. The role of microRNAs in mitochondria in cancer. Cancer Letters. OXFORD: ELSEVIER, 2013, vol. 336, No 1, p. 1-7. ISSN 0304-3835. Available from: https://dx.doi.org/10.1016/j.canlet.2013.05.001.
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Basic information
Original name The role of microRNAs in mitochondria in cancer
Authors BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, belonging to the institution), Jiří ŠÁNA (203 Czech Republic, belonging to the institution) and Ondřej SLABÝ (203 Czech Republic, guarantor, belonging to the institution).
Edition Cancer Letters, OXFORD, ELSEVIER, 2013, 0304-3835.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 5.016
RIV identification code RIV/00216224:14740/13:00065603
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1016/j.canlet.2013.05.001
UT WoS 000321477800001
Keywords in English microRNA; mitochondria; Krebs cycle; apoptosis; mitophagy
Tags rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 5/4/2014 17:13.
Abstract
Reprogramming of the energy metabolism in cancer cell presents progressive field of cancer research. This feature is associated mainly with the mitochondria, which is major energy source of eukaryotic cells. These organelles are essential to the cell homeostasis maintenance, play an important role in intrinsic apoptotic pathway and their dysfunction is associated with multiple diseases including cancer. Recently, it was described that microRNAs (miRNAs) regulate important signaling pathways in mitochondria and many of these miRNAs are deregulated in various cancers. Here we summarize current knowledge about miRNAs involved in mitochondrial functioning with focus on cellular energy metabolism, apoptosis and mitophagy.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
NT13514, research and development projectName: Analýza mikroRNA v glioblastomových kmenových buňkách: predikce léčebné odpovědi a identifikace nových terapeutických cílů u pacientů s glioblastomem
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