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@proceedings{1116977,
author = {Gelbíčová, Tereza and Karpíšková, Renata},
booktitle = {FEMS 2013 - the 5th congress of European microbiologists},
keywords = {listeria; antimicrobial susceptibility; clinical isolates},
language = {eng},
title = {Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in the Czech Republic},
year = {2013}
}
TY - CONF
ID - 1116977
AU - Gelbíčová, Tereza - Karpíšková, Renata
PY - 2013
TI - Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in the Czech Republic
KW - listeria
KW - antimicrobial susceptibility
KW - clinical isolates
N2 - Listeria monocytogenes is generally susceptible to a wide range of antimicrobials. However resistant or multidrug-resistant strains of L. monocytogens isolated from human, food or environment were reported, too. The aim of this study was to observe whether the susceptibility of L. monocytogenes of human origin has changed in the period from 2001 to 2012 in the Czech Republic. In total, 169 human strains isolated from different regions of the Czech Republic were tested. Strains originated from blood cultures (83), cerebrospinal fluid (28) and other material (58) like newborns, liver, etc. Phenotypic resistance testing has been performed by the disk diffusion method according to the Clinical and Laboratory Standards Institute (CLSI, 2006). Following antimicrobial agents were tested: ampicillin, penicillin, erythromycin, gentamicin, trimethoprim, vancomycin, tetracyclin and chloramfenicol. The zone diametr breakpoints for Staphylococcus spp. were applied with the exception for penicillin and ampicillin for these agents criteria for Enterococcus spp. were applied (CLSI, 2006). None of the tested strains revealed resistance to the tested panel of antimicrobial agents, all strains showed good sensitivity to drugs used for treatment of listeria infections. Since the year 2012 EUCAST has recommended clinical MICs and zone diameters of L. monocytogenes for antibiotics use in human therapy. This fact can help to compare results of antibiotic susceptibility of L. monocytogenes between various studies on international level. Our results indicate very good susceptibility of human strains of L. monocytogenes to antimicrobials used in the treatment of human listeriosis in the Czech Republic during the monitoring period.
ER -
GELBÍČOVÁ, Tereza a Renata KARPÍŠKOVÁ. Antimicrobial resistance of Listeria monocytogenes strains isolated from humans in the Czech Republic. In \textit{FEMS 2013 - the 5th congress of European microbiologists}. 2013.
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