2012
Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles
CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ et. al.Základní údaje
Originální název
Novel Electrochemical Biosensor for Simultaneous Detection of Adenine and Guanine Based on Cu2O Nanoparticles
Autoři
CHOMOUCKA, Jana, Jan PRASEK, Petra BUSINOVA, Libuše TRNKOVÁ, Jana DRBOHLAVOVÁ, Jan PEKAREK, Radim HRDY a Jaromír HUBÁLEK
Vydání
47. vyd. Amsterdam, 26th European Conference on Solid-State Transducers, EUROSENSOR 2012, od s. 702-705, 4 s. 2012
Nakladatel
ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Další údaje
Jazyk
angličtina
Typ výsledku
Stať ve sborníku
Obor
10403 Physical chemistry
Stát vydavatele
Nizozemské království
Utajení
není předmětem státního či obchodního tajemství
Forma vydání
tištěná verze "print"
Organizační jednotka
Přírodovědecká fakulta
ISSN
UT WoS
000312953300175
Klíčová slova anglicky
Thick film technology; electrochemistry; cyclic voltametry; copper(I) oxide; purines
Změněno: 29. 4. 2014 16:55, Ing. Andrea Mikešková
Anotace
V originále
In this paper Cu2O nanoparticles were prepared and used for the construction of novel electrochemical voltammetric biosensor for the simultaneous detection of adenine and guanine. Cu2O nanoparticles were synthesized via simple wet chemical route, where glucose was used as a reductant. The nanoparticles were characterized by SEM and XRD analysis, which showed the presence of spherical aggregations with diameter of 1000 nm. These nanoparticles were successfully used for fabrication of spray-coated and screen-printed working electrodes on alumina substrate for the electrochemical detection of purine bases. We observed that Cu(I) reacts with adenine to form insoluble complex that accumulates on the electrode surface and causes the decrease of current response. In the case of guanine, we did not observed any significant decrease of current response which is probably caused by adsorption of guanine on the electrode surface.
Návaznosti
MUNI/A/0992/2009, interní kód MU |
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