| KAZDA, Tomáš, Petr POSPÍŠIL, Hana DOLEŽELOVÁ, Radim JANČÁLEK a Pavel ŠLAMPA. Whole brain radiotherapy: Consequences for personalized medicine. Reports of Practical Oncology and Radiotherapy. 2013, roč. 18, č. 3, s. 133-138. ISSN 1507-1367. Dostupné z: https://dx.doi.org/10.1016/j.rpor.2013.03.002. |
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@article{1123320,
author = {Kazda, Tomáš and Pospíšil, Petr and Doleželová, Hana and Jančálek, Radim and Šlampa, Pavel},
article_number = {3},
doi = {http://dx.doi.org/10.1016/j.rpor.2013.03.002},
keywords = {Brain metastases; Decision-making; Personalized medicine; Whole brain radiotherapy},
language = {eng},
issn = {1507-1367},
journal = {Reports of Practical Oncology and Radiotherapy},
title = {Whole brain radiotherapy: Consequences for personalized medicine},
volume = {18},
year = {2013}
}
TY - JOUR
ID - 1123320
AU - Kazda, Tomáš - Pospíšil, Petr - Doleželová, Hana - Jančálek, Radim - Šlampa, Pavel
PY - 2013
TI - Whole brain radiotherapy: Consequences for personalized medicine
JF - Reports of Practical Oncology and Radiotherapy
VL - 18
IS - 3
SP - 133-138
EP - 133-138
SN - 15071367
KW - Brain metastases
KW - Decision-making
KW - Personalized medicine
KW - Whole brain radiotherapy
N2 - Several studies focusing on brain irradiation are in progress. Reflecting updates of relevant outcomes in palliative treatment of patients suffering from brain metastases, the primary objective of these studies is the evaluation of neurocognitive function and quality of life. Improvements of technology in radiation oncology allows us to spare the hippocampal region while appropriately irradiating other parts of brain tissue. Irradiation of the hippocampus region is likely to lead to manifestations of adverse events with a subsequent impact on patient's quality of life, which is in fact an improper approach in palliative medicine. Ongoing studies evaluate results of hippocampus avoiding radiotherapy compared to standard whole brain radiotherapy. Incorporation of neurocognitive function assessment may result in the confirmation of superiority of sparing the region of hippocampus and thus change current style of providing brain irradiation.
ER -
KAZDA, Tomáš, Petr POSPÍŠIL, Hana DOLEŽELOVÁ, Radim JANČÁLEK a Pavel ŠLAMPA. Whole brain radiotherapy: Consequences for personalized medicine. \textit{Reports of Practical Oncology and Radiotherapy}. 2013, roč.~18, č.~3, s.~133-138. ISSN~1507-1367. Dostupné z: https://dx.doi.org/10.1016/j.rpor.2013.03.002.
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