The enigma of eugregarine epicytic folds: Where gliding
motility originates?

J 2013

The enigma of eugregarine epicytic folds: Where gliding motility originates?

VALIGUROVÁ, Andrea, Naděžda VAŠKOVICOVÁ, Naďa MUSILOVÁ a Joseph SCHREVEL

Základní údaje

Originální název

The enigma of eugregarine epicytic folds: Where gliding motility originates?

Název česky

The enigma of eugregarine epicytic folds: Where gliding motility originates?

Autoři

VALIGUROVÁ, Andrea (703 Slovensko, garant, domácí), Naděžda VAŠKOVICOVÁ (203 Česká republika, domácí), Naďa MUSILOVÁ (203 Česká republika, domácí) a Joseph SCHREVEL (250 Francie)

Vydání

Frontiers in Zoology, 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8, BIOMED CENTRAL LTD, 2013, 1742-9994

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.304

Kód RIV

RIV/00216224:14310/13:00066463

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1186/1742-9994-10-57

UT WoS

000325314300001

Klíčová slova česky

Actin; Cytochalasin D; Epicyte; Epicytic folds; Eugregarine; Glideosome; Gliding motility; Jasplakinolide; Mucus; Myosin; Pellicle

Klíčová slova anglicky

Actin; Cytochalasin D; Epicyte; Epicytic folds; Eugregarine; Glideosome; Gliding motility; Jasplakinolide; Mucus; Myosin; Pellicle

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 3. 2018 15:06, Mgr. Lucie Jarošová, DiS.

Anotace

V originále

Gregarines (Conoidasida, Gregarinasina) are a heterogeneous group that parasitize invertebrates and urochordates, and are thought to be an early branching lineage of Apicomplexa. As characteristic of apicomplexan zoites, gregarines are covered by a complicated pellicle, consisting of the plasma membrane and the closely apposed inner membrane complex, associated with cytoskeletal elements. The cell cortex of eugregarines, the epicyte, is more complicated than that of other apicomplexans, as it forms various superficial structures. The epicyte of the eugregarines, Gregarina cuneata, G. polymorpha and G. steini, analysed in the present study is organised in longitudinal folds covering the entire cell. In mature trophozoites and gamonts, each epicytic fold exhibits similar ectoplasmic structures and is built up from the plasma membrane, inner membrane complex, 12-nm filaments, rippled dense structures and basal lamina. In addition, rib-like myonemes and an ectoplasmic network are frequently observed. Under experimental conditions, eugregarines showed varied speeds and paths of simple linear gliding. In all three species, actin and myosin were associated with the pellicle, and this actomyosin complex appeared to be restricted to the lateral parts of the epicytic folds. Treatment of living gamonts with jasplakinolide and cytochalasin D confirmed that actin actively participates in gregarine gliding. Contributions to gliding of specific subcellular components are discussed. Cell motility in gregarines and other apicomplexans share features in common, i.e. a three-layered pellicle, an actomyosin complex, and the polymerisation of actin during gliding. Although the general architecture and supramolecular organisation of the pellicle is not correlated with gliding rates of eugregarines, an increase in cytoplasmic mucus concentration is correlated. Data suggest that gregarines utilize several mechanisms of motility and that this is influenced by environmental conditions.

Návaznosti

GPP506/10/P372, projekt VaV

Název: Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa

Investor: Grantová agentura ČR, Srovnávací morfologie a imunohistochemie v hodnocení fylogenetických vztahů mezi zástupci raných linií kmene Apicomplexa

Citovat

VALIGUROVÁ, Andrea, Naděžda VAŠKOVICOVÁ, Naďa MUSILOVÁ a Joseph SCHREVEL. The enigma of eugregarine epicytic folds: Where gliding motility originates? Frontiers in Zoology. 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8: BIOMED CENTRAL LTD, 2013, roč. 10, č. 10, s. 57-83. ISSN 1742-9994. Dostupné z: https://dx.doi.org/10.1186/1742-9994-10-57.

@article{1126969,
   author = {Valigurová, Andrea and Vaškovicová, Naděžda and Musilová, Naďa and Schrevel, Joseph},
   article_location = {236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8},
   article_number = {10},
   doi = {http://dx.doi.org/10.1186/1742-9994-10-57},
   keywords = {Actin; Cytochalasin D; Epicyte; Epicytic folds; Eugregarine; Glideosome; Gliding motility; Jasplakinolide; Mucus; Myosin; Pellicle},
   language = {eng},
   issn = {1742-9994},
   journal = {Frontiers in Zoology},
   title = {The enigma of eugregarine epicytic folds: Where gliding motility originates?},
   url = {http://www.frontiersinzoology.com/content/10/1/57/abstract},
   volume = {10},
   year = {2013}
}

TY  - JOUR
ID  - 1126969
AU  - Valigurová, Andrea - Vaškovicová, Naděžda - Musilová, Naďa - Schrevel, Joseph
PY  - 2013
TI  - The enigma of eugregarine epicytic folds: Where gliding motility originates?
JF  - Frontiers in Zoology
VL  - 10
IS  - 10
SP  - 57
EP  - 57
PB  - BIOMED CENTRAL LTD
SN  - 17429994
KW  - Actin
KW  - Cytochalasin D
KW  - Epicyte
KW  - Epicytic folds
KW  - Eugregarine
KW  - Glideosome
KW  - Gliding motility
KW  - Jasplakinolide
KW  - Mucus
KW  - Myosin
KW  - Pellicle
UR  - http://www.frontiersinzoology.com/content/10/1/57/abstract
L2  - http://www.frontiersinzoology.com/content/10/1/57/abstract
N2  - Gregarines (Conoidasida, Gregarinasina) are a heterogeneous group that parasitize invertebrates and urochordates, and are thought to be an early branching lineage of Apicomplexa. As characteristic of apicomplexan zoites, gregarines are covered by a complicated pellicle, consisting of the plasma membrane and the closely apposed inner membrane complex, associated with cytoskeletal elements. The cell cortex of eugregarines, the epicyte, is more complicated than that of other apicomplexans, as it forms various superficial structures. The epicyte of the eugregarines, Gregarina cuneata, G. polymorpha and G. steini, analysed in the present study is organised in longitudinal folds covering the entire cell. In mature trophozoites and gamonts, each epicytic fold exhibits similar ectoplasmic structures and is built up from the plasma membrane, inner membrane complex, 12-nm filaments, rippled dense structures and basal lamina. In addition, rib-like myonemes and an ectoplasmic network are frequently observed. Under experimental conditions, eugregarines showed varied speeds and paths of simple linear gliding. In all three species, actin and myosin were associated with the pellicle, and this actomyosin complex appeared to be restricted to the lateral parts of the epicytic folds. Treatment of living gamonts with jasplakinolide and cytochalasin D confirmed that actin actively participates in gregarine gliding. Contributions to gliding of specific subcellular components are discussed. Cell motility in gregarines and other apicomplexans share features in common, i.e. a three-layered pellicle, an actomyosin complex, and the polymerisation of actin during gliding. Although the general architecture and supramolecular organisation of the pellicle is not correlated with gliding rates of eugregarines, an increase in cytoplasmic mucus concentration is correlated. Data suggest that gregarines utilize several mechanisms of motility and that this is influenced by environmental conditions.
ER  -

VALIGUROVÁ, Andrea, Naděžda VAŠKOVICOVÁ, Naďa MUSILOVÁ a Joseph SCHREVEL. The enigma of eugregarine epicytic folds: Where gliding motility originates? \textit{Frontiers in Zoology}. 236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8: BIOMED CENTRAL LTD, 2013, roč.~10, č.~10, s.~57-83. ISSN~1742-9994. Dostupné z: https://dx.doi.org/10.1186/1742-9994-10-57.

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