| RÁJECKÝ, Michal, Iva SLANINOVÁ, Petra MOKRIŠOVÁ, Jana URBANOVÁ, Martin PALKOVSKÝ, Eva TÁBORSKÁ a Petr TÁBORSKÝ. Alkaloid chelirubine and DNA: Blue and red luminescence. Talanta. Amsterdam: Elsevier Science, 2013, roč. 105, únor, s. 317-319. ISSN 0039-9140. Dostupné z: https://dx.doi.org/10.1016/j.talanta.2012.10.045. |
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@article{1131043,
author = {Rájecký, Michal and Slaninová, Iva and Mokrišová, Petra and Urbanová, Jana and Palkovský, Martin and Táborská, Eva and Táborský, Petr},
article_location = {Amsterdam},
article_number = {únor},
doi = {http://dx.doi.org/10.1016/j.talanta.2012.10.045},
keywords = {Alkaloid; Benzo[c]phenanthridine; Chelirubine; DNA; Intercalation; Fluorescence},
language = {eng},
issn = {0039-9140},
journal = {Talanta},
title = {Alkaloid chelirubine and DNA: Blue and red luminescence},
url = {http://www.sciencedirect.com/science/article/pii/S0039914012008764},
volume = {105},
year = {2013}
}
TY - JOUR
ID - 1131043
AU - Rájecký, Michal - Slaninová, Iva - Mokrišová, Petra - Urbanová, Jana - Palkovský, Martin - Táborská, Eva - Táborský, Petr
PY - 2013
TI - Alkaloid chelirubine and DNA: Blue and red luminescence
JF - Talanta
VL - 105
IS - únor
SP - 317-319
EP - 317-319
PB - Elsevier Science
SN - 00399140
KW - Alkaloid
KW - Benzo[c]phenanthridine
KW - Chelirubine
KW - DNA
KW - Intercalation
KW - Fluorescence
UR - http://www.sciencedirect.com/science/article/pii/S0039914012008764
L2 - http://www.sciencedirect.com/science/article/pii/S0039914012008764
N2 - Extracts from Himalayan herb Dicranostigma lactucoides containing alkaloid chelirubine have been used for centuries in Chinese herbal medicine. We have found a new employment for the alkaloid: it can be used as a DNA fluorescent probe showing blue (free form) and red (intercalated to DNA) luminescence emission after irradiation by violet light. Besides quantification of DNA (LOD = 6 ng.ml-1) it can also be used as a supravital cell probe because chelirubine molecules can effectively enter to the living cell through the cell membrane.
ER -
RÁJECKÝ, Michal, Iva SLANINOVÁ, Petra MOKRIŠOVÁ, Jana URBANOVÁ, Martin PALKOVSKÝ, Eva TÁBORSKÁ a Petr TÁBORSKÝ. Alkaloid chelirubine and DNA: Blue and red luminescence. \textit{Talanta}. Amsterdam: Elsevier Science, 2013, roč.~105, únor, s.~317-319. ISSN~0039-9140. Dostupné z: https://dx.doi.org/10.1016/j.talanta.2012.10.045.
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