2013
Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors
SOŠKA, Vladimír; Michaela FRANTISOVÁ; Petr DOBŠÁK; Ladislav DUŠEK; Jiří JARKOVSKÝ et al.Základní údaje
Originální název
Cardio-Ankle Vascular Index in Subjects with Dyslipidaemia and Other Cardiovascular Risk Factors
Autoři
SOŠKA, Vladimír; Michaela FRANTISOVÁ; Petr DOBŠÁK; Ladislav DUŠEK; Jiří JARKOVSKÝ ORCID; Marie NOVÁKOVÁ; Kohji SHIRAI; Lenka FAJKUSOVÁ a Tomáš FREIBERGER ORCID
Vydání
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS, TOKYO, JAPAN ATHEROSCLEROSIS SOC, 2013, 1340-3478
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30201 Cardiac and Cardiovascular systems
Stát vydavatele
Japonsko
Utajení
není předmětem státního či obchodního tajemství
Impakt faktor
Impact factor: 2.770
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14110/13:00070319
Organizační jednotka
Lékařská fakulta
UT WoS
Klíčová slova anglicky
Dyslipidaemia; Cardio-ankle vascular index; Hypertension; Diabetes mellitus; Smoking
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 29. 4. 2014 14:24, Ing. Mgr. Věra Pospíšilíková
Anotace
V originále
Aim: The cardio-ankle vascular index (CAVI) is a novel non-invasive marker of arterial stiffness and atherosclerosis. The aim of this work was to examine whether the CAVI value in patients with dyslipidaemia (DLP) is increased by the presence of other cardiovascular risk factors: hypertension, diabetes mellitus, and smoking. Methods: A total of 392 subjects with DLP (166 male, 226 female), with a median age of 58.5 and 5-95 percentile range 32.2-73.9 years were examined. CAVI was measured using the VaSera 1500 system. Results: CAVI correlated significantly with age (p<0.001) and both systolic (p<0.001) and diastolic (p=0.002) blood pressure; higher values were found in men (p=0.034) than in women in the 56-65 age group. There was no significant difference in CAVI between smokers and non-smokers (p=0.217) and between subjects with and without diabetes mellitus (p=0.424). CAVI was significantly higher in subjects with hypertension than in the normotensive group (p<0.001) and in statin-treated subjects than in those without statins (p<0.001); however, CAVI values adjusted for age and sex did not differ significantly between these groups. Adjusted CAVI values were higher only in smokers than in non-smokers (former smokers) (p<0.001). Conclusion: The study proves conclusively that the CAVI value in DLP patients is not significantly affected by hypertension and diabetes mellitus, but it is increased by smoking.