In vitro effects of pollutants from particulate and volatile
fractions of air samples-day and night variability

J 2013

In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability

NOVÁK, Jiří, J.P. GIESY, Jana KLÁNOVÁ a Klára HILSCHEROVÁ

Základní údaje

Originální název

In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability

Autoři

NOVÁK, Jiří (203 Česká republika, garant, domácí), J.P. GIESY (124 Kanada), Jana KLÁNOVÁ (203 Česká republika, domácí) a Klára HILSCHEROVÁ (203 Česká republika, domácí)

Vydání

Environmental Science and Pollution Research, Landsberg, Germany, Ecomed, 2013, 0944-1344

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10511 Environmental sciences

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.757

Kód RIV

RIV/00216224:14310/13:00066746

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1007/s11356-013-1726-6

UT WoS

000322155400069

Klíčová slova anglicky

Ambient air; Particulate matter; Gas phase; AhR-mediated toxicity; Estrogenicity; Androgenicity

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 4. 4. 2014 13:56, Ing. Andrea Mikešková

Anotace

V originále

Chemicals in air were characterized for potential interference with signaling of estrogen, androgen, and arylhydrocarbon (AhR) receptors, which are known to play an important role in endocrine-disruptive changes in vivo. Previously, effects of this type have been studied mainly in particulate matter in the ambient air from various localities. In this study, both volatile and particulate fractions of air from three sites in Banja Luka region (Bosnia and Herzegovina) were investigated to describe the distribution of endocrine-disrupting contaminants on a small spatial scale. Circadian variability of air pollution was investigated by collecting samples during both day and night. Air samples collected from urban localities at night were more potent in producing the AhR-mediated effects than those collected during daytime. This trend was not observed at the reference rural location. None of the samples showed significant estrogenic or androgenic activity. On the other hand, anti-androgenicity was detected in both particulate and vapor phases, while anti-estrogenicity was detected only in the particulate fraction of air from all localities. The AhR-mediated potencies of samples were associated primarily with non-persistent compounds. Based on the concentrations of 28 individual compounds, PAHs accounted for approximately 30 % of the AhR-mediated potency determined by the bioassay. The results show that there can be a significant difference between levels of bioactive compounds in air between daytime and nighttime

Návaznosti

ED0001/01/01, projekt VaV

Název: CETOCOEN

GPP503/10/P249, projekt VaV

Název: Stanovení sady biologických efektů atmosferických polutantů in vitro

Investor: Grantová agentura ČR, Stanovení sady biologických efektů atmosferických polutantů in vitro

2B08036, projekt VaV

Název: Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů (Akronym: ENVISCREEN)

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Nové molekulárně biologické a biochemické metody pro monitoring estrogenů a dalších chemických endokrinních disruptorů

Citovat

NOVÁK, Jiří, J.P. GIESY, Jana KLÁNOVÁ a Klára HILSCHEROVÁ. In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability. Environmental Science and Pollution Research. Landsberg, Germany: Ecomed, 2013, roč. 20, č. 9, s. 6620-6627. ISSN 0944-1344. Dostupné z: https://dx.doi.org/10.1007/s11356-013-1726-6.

@article{1159461,
   author = {Novák, Jiří and Giesy, J.P. and Klánová, Jana and Hilscherová, Klára},
   article_location = {Landsberg, Germany},
   article_number = {9},
   doi = {http://dx.doi.org/10.1007/s11356-013-1726-6},
   keywords = {Ambient air; Particulate matter; Gas phase; AhR-mediated toxicity; Estrogenicity; Androgenicity},
   language = {eng},
   issn = {0944-1344},
   journal = {Environmental Science and Pollution Research},
   title = {In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability},
   volume = {20},
   year = {2013}
}

TY  - JOUR
ID  - 1159461
AU  - Novák, Jiří - Giesy, J.P. - Klánová, Jana - Hilscherová, Klára
PY  - 2013
TI  - In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability
JF  - Environmental Science and Pollution Research
VL  - 20
IS  - 9
SP  - 6620-6627
EP  - 6620-6627
PB  - Ecomed
SN  - 09441344
KW  - Ambient air
KW  - Particulate matter
KW  - Gas phase
KW  - AhR-mediated toxicity
KW  - Estrogenicity
KW  - Androgenicity
N2  - Chemicals in air were characterized for potential interference with signaling of estrogen, androgen, and arylhydrocarbon (AhR) receptors, which are known to play an important role in endocrine-disruptive changes in vivo. Previously, effects of this type have been studied mainly in particulate matter in the ambient air from various localities. In this study, both volatile and particulate fractions of air from three sites in Banja Luka region (Bosnia and Herzegovina) were investigated to describe the distribution of endocrine-disrupting contaminants on a small spatial scale. Circadian variability of air pollution was investigated by collecting samples during both day and night. Air samples collected from urban localities at night were more potent in producing the AhR-mediated effects than those collected during daytime. This trend was not observed at the reference rural location. None of the samples showed significant estrogenic or androgenic activity. On the other hand, anti-androgenicity was detected in both particulate and vapor phases, while anti-estrogenicity was detected only in the particulate fraction of air from all localities. The AhR-mediated potencies of samples were associated primarily with non-persistent compounds. Based on the concentrations of 28 individual compounds, PAHs accounted for approximately 30 % of the AhR-mediated potency determined by the bioassay. The results show that there can be a significant difference between levels of bioactive compounds in air between daytime and nighttime
ER  -

NOVÁK, Jiří, J.P. GIESY, Jana KLÁNOVÁ a Klára HILSCHEROVÁ. In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability. \textit{Environmental Science and Pollution Research}. Landsberg, Germany: Ecomed, 2013, roč.~20, č.~9, s.~6620-6627. ISSN~0944-1344. Dostupné z: https://dx.doi.org/10.1007/s11356-013-1726-6.

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