Zobrazovací metody v diagnostice kolorektálního karcinomu

BOHATÁ, Šárka; Daniel BARTUŠEK; Beáta HEMMELOVÁ and Vlastimil VÁLEK. Zobrazovací metody v diagnostice kolorektálního karcinomu (Imaging methods in colorectal cancer diagnostics). Farmakoterapie. Farmakon Press s.r.o., 2013, vol. 9, "Kolorektální karcinom", p. 12-18. ISSN 1801-1209.

Basic information

Original name

Zobrazovací metody v diagnostice kolorektálního karcinomu

Name (in English)

Imaging methods in colorectal cancer diagnostics

Authors

BOHATÁ, Šárka (203 Czech Republic, guarantor, belonging to the institution); Daniel BARTUŠEK (203 Czech Republic, belonging to the institution); Beáta HEMMELOVÁ (203 Czech Republic, belonging to the institution) and Vlastimil VÁLEK (203 Czech Republic, belonging to the institution)

Edition

Farmakoterapie, Farmakon Press s.r.o. 2013, 1801-1209

---

Other information

Language

Czech

Type of outcome

Article in a journal

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Czech Republic

Confidentiality degree

is not subject to a state or trade secret

RIV identification code

RIV/00216224:14110/13:00071646

Organization unit

Faculty of Medicine

Keywords in English

ultrasound; endoanal ultrasound; computerized tomography; magnetic resonance; rectal cancer; staging

---

Abstract

V originále

Včasná a správná diagnóza, stejně jako přesný staging jsou pro stanovení optimální léčby kolorektálního karcinomu klíčové a také určují prognózu. Na poli diagnostiky, respektive stagingu, se v současnosti uplatňuje několik metod, z nichž každá má své limitace, proto je většinou potřeba je navzájem kombinovat.

In English

In management of rectal cancer preoperative investigations assist in deciding the optimal treatment. The relation of the tumor edge to the circumferential margin is an important factor in deciding the need for neoadjuvant treatment and determines the prognosis. Those with threatened or involved margins are offered long course chemoradiation to enable R0 surgical resection. Endoanal ultrasound is useful for tumor (T) staging; hence it is a useful imaging modality for early rectal cancer. Magnetic resonance imaging (MRI) is useful for assessing the mesorectum and the mesorectal fascia which has useful prognostic significance and for early identification of local recurrence. Computerized tomography (CT) of the chest, abdomen and pelvis is used to rule out distant metastasis. Identification of the malignant nodes using EUS, CT and MRI is based on the size, morphology and internal characteristics but has drawbacks. Most of the common imaging techniques are suboptimal for imaging following chemoradiation as they struggle to differentiate fibrotic changes and tumor. In this situation, EUS and MRI may provide complementary information to decide further treatment. The article summarize indications, advantages and pitfalls of each imaging method.