PRACHÁR, Patrik, Sonia BARTÁKOVÁ, Vítězslav BŘEZINA, L. CVRČEK and Jiří VANĚK. Cytocompatibility of implants coated with titanium nitride and zirconium nitride. Bratislavské lekárské listy. Bratislava: Veda, 2015, vol. 116, No 3, p. 154-156. ISSN 0006-9248. Available from: https://dx.doi.org/10.4149/BLL_2015_031.
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Basic information
Original name Cytocompatibility of implants coated with titanium nitride and zirconium nitride
Name in Czech Cytokompatibilta implantátů povlakovaných vrstvami nitrudu titanu a nitridu zirconia
Name (in English) Cytocompatibility of implants coated with titanium nitride and zirconium nitride
Authors PRACHÁR, Patrik (203 Czech Republic, guarantor, belonging to the institution), Sonia BARTÁKOVÁ (203 Czech Republic, belonging to the institution), Vítězslav BŘEZINA (203 Czech Republic, belonging to the institution), L. CVRČEK (203 Czech Republic) and Jiří VANĚK (203 Czech Republic, belonging to the institution).
Edition Bratislavské lekárské listy, Bratislava, Veda, 2015, 0006-9248.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.454
RIV identification code RIV/00216224:14110/15:00081973
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.4149/BLL_2015_031
UT WoS 000351248700004
Keywords (in Czech) nitrid titanu; nitrid zirconia; cytokompatibilita; biokeramika
Keywords in English titanium nitride; zirconium nitride; coatings; cytocompatibility; bioceramics
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 9/11/2015 10:49.
Abstract
Introduction: Cytocompatibility (response of cells to the tested material and their capacity to recover all their physiological functions) is critical for implants besides their mechanical and physical properties. The positive cell response to the implant material is reflected by the capacity of cells to divide, which leads to the tissue regeneration and osseointegration. Technically pure titanium and its alloys are mostly used for implant manufacturing. These alloys have the adequate mechanical, physical and biological properties; nevertheless, the superior biocompatibility of bioceramics has been proven. With the arrival of new coating techniques, surface modification of materials used for implants has become a widely investigated issue. Methods: The paper studied properties of titanium nitride (TiN) and zirconium nitride (ZrN) coatings deposited by PVD (Physical Vapour Deposition). Coatings were applied to substrates of pure titanium, Ti6Al4V, Ti35Nb6Ta titanium alloys and CoCrMo dental alloy. Different treatments of substrate surfaces were used: polishing, etching and grit blasting. Cytocompatibility tests assessed the cell colonization and their adherence to substrates. Results and Conclusion: Results showed that TiN layers deposited by PVD are suitable for coating all substrates studied. The polished samples and those with TiN coating exhibited higher cell colonization. This coating technique meets the requirements for the biocompatibility of the implanted materials; furthermore, their color range solves the issue of red aesthetics in oral implantology as the color of these coatings prevents titanium from showing through the gingiva. This is one the most important criteria for the aesthetic success of implant therapy.
Abstract (in English)
Introduction: Cytocompatibility (response of cells to the tested material and their capacity to recover all their physiological functions) is critical for implants besides their mechanical and physical properties. The positive cell response to the implant material is reflected by the capacity of cells to divide, which leads to the tissue regeneration and osseointegration. Technically pure titanium and its alloys are mostly used for implant manufacturing. These alloys have the adequate mechanical, physical and biological properties; nevertheless, the superior biocompatibility of bioceramics has been proven. With the arrival of new coating techniques, surface modification of materials used for implants has become a widely investigated issue. Methods: The paper studied properties of titanium nitride (TiN) and zirconium nitride (ZrN) coatings deposited by PVD (Physical Vapour Deposition). Coatings were applied to substrates of pure titanium, Ti6Al4V, Ti35Nb6Ta titanium alloys and CoCrMo dental alloy. Different treatments of substrate surfaces were used: polishing, etching and grit blasting. Cytocompatibility tests assessed the cell colonization and their adherence to substrates. Results and Conclusion: Results showed that TiN layers deposited by PVD are suitable for coating all substrates studied. The polished samples and those with TiN coating exhibited higher cell colonization. This coating technique meets the requirements for the biocompatibility of the implanted materials; furthermore, their color range solves the issue of red aesthetics in oral implantology as the color of these coatings prevents titanium from showing through the gingiva. This is one the most important criteria for the aesthetic success of implant therapy.
Links
1M0528, research and development projectName: Stomatologické výzkumné centrum
Investor: Ministry of Education, Youth and Sports of the CR, Dental research centre
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