MHC genes and parasitism in Carassius gibelio, a
diploid-triploid fish species with dual reproduction strategies

J 2013

MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Martin KOŠAŘ, Lukáš VETEŠNÍK a Martina MRKVICOVÁ

Základní údaje

Originální název

MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies

Autoři

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea (203 Česká republika, garant, domácí), Martin KOŠAŘ (203 Česká republika, domácí), Lukáš VETEŠNÍK (203 Česká republika) a Martina MRKVICOVÁ (203 Česká republika, domácí)

Vydání

BMC Evolutionary Biology, BioMed Central, 2013, 1471-2148

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10600 1.6 Biological sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 3.407

Kód RIV

RIV/00216224:14310/13:00066956

Organizační jednotka

Přírodovědecká fakulta

DOI

http://dx.doi.org/10.1186/1471-2148-13-122

UT WoS

000320774400001

Klíčová slova anglicky

gynogenesis; sexual reproduction; polyploid fish; MHC; coexistence; parasitism

Štítky

AKR, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 8. 3. 2018 15:43, Mgr. Lucie Jarošová, DiS.

Anotace

V originále

Background The gibel carp is a fish species with dual reproduction modes, gynogenesis and sexual reproduction, coexisting in mixed diploid-polyploid populations. Following the Red Queen (RQ) assumption, asexual organisms are, due to their low genetic diversity, targets for parasite adaptation. Because MHC polymorphism is maintained by selection from parasites and sexual selection, MHC genes are considered as a suitable candidate for testing the RQ hypothesis. In this study, we investigated MHC variability and the selection pressure acting on MHC genes in sexual diploids and asexual triploids. In addition, we tested whether the asexual form of gibel carp suffers from higher parasite loads than the sexual form. Results At the population level, genotype and allelic diversity of MHC were reduced in gynogenetic triploids when compared to sexual diploids. Different patterns in positively selected sites (PSS) between gynogens and sexual gibel carp were also found. A weak difference in parasite species richness was found between sexual fish and gynogens. However, two common clones of gynogens were significantly more parasitized than sexual diploids or other gynogens with rare MHC genotypes. At the individual level, the higher number of alleles was not associated with higher parasitism in either sexual diploids or gynogens. Conclusions The differences in MHC diversity between gynogenetic triploids and sexual diploids are in accordance with the hypothesis of sexually-mediated selection increasing MHC diversity and fulfil a prerequisite of the Red Queen hypothesis. The different patterns in PPS between gynogens and sexual gibel carp also suggest the potential role of sexual selection and supports parasite-mediated selection maintaining MHC diversity. We showed that the most common MHC genotypes of gynogenetic triploids are the target of parasite selection. Our results suggest that the MHC genotype in gibel carp is more important than allelic number for immunocompetence.

Návaznosti

GAP505/12/0375, projekt VaV

Název: Evolučně-imunitní a ekologické aspekty parazitace u hybridních a polyploidních kaprovitých ryb

Investor: Grantová agentura ČR, Evolučně-imunitní a ekologické aspekty parazitace u hybridních a polypoidních kaprovitých ryb

Citovat

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Martin KOŠAŘ, Lukáš VETEŠNÍK a Martina MRKVICOVÁ. MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies. BMC Evolutionary Biology. BioMed Central, 2013, roč. 13, JUN 14 2013, s. 122-136. ISSN 1471-2148. Dostupné z: https://dx.doi.org/10.1186/1471-2148-13-122.

@article{1168141,
   author = {Vetešníková Šimková, Andrea and Košař, Martin and Vetešník, Lukáš and Mrkvicová, Martina},
   article_number = {JUN 14 2013},
   doi = {http://dx.doi.org/10.1186/1471-2148-13-122},
   keywords = {gynogenesis; sexual reproduction; polyploid fish; MHC; coexistence; parasitism},
   language = {eng},
   issn = {1471-2148},
   journal = {BMC Evolutionary Biology},
   title = {MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies},
   volume = {13},
   year = {2013}
}

TY  - JOUR
ID  - 1168141
AU  - Vetešníková Šimková, Andrea - Košař, Martin - Vetešník, Lukáš - Mrkvicová, Martina
PY  - 2013
TI  - MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies
JF  - BMC Evolutionary Biology
VL  - 13
IS  - JUN 14 2013
SP  - 122
EP  - 122
PB  - BioMed Central
SN  - 14712148
KW  - gynogenesis
KW  - sexual reproduction
KW  - polyploid fish
KW  - MHC
KW  - coexistence
KW  - parasitism
N2  - Background The gibel carp is a fish species with dual reproduction modes, gynogenesis and sexual reproduction, coexisting in mixed diploid-polyploid populations. Following the Red Queen (RQ) assumption, asexual organisms are, due to their low genetic diversity, targets for parasite adaptation. Because MHC polymorphism is maintained by selection from parasites and sexual selection, MHC genes are considered as a suitable candidate for testing the RQ hypothesis. In this study, we investigated MHC variability and the selection pressure acting on MHC genes in sexual diploids and asexual triploids. In addition, we tested whether the asexual form of gibel carp suffers from higher parasite loads than the sexual form. Results At the population level, genotype and allelic diversity of MHC were reduced in gynogenetic triploids when compared to sexual diploids. Different patterns in positively selected sites (PSS) between gynogens and sexual gibel carp were also found. A weak difference in parasite species richness was found between sexual fish and gynogens. However, two common clones of gynogens were significantly more parasitized than sexual diploids or other gynogens with rare MHC genotypes. At the individual level, the higher number of alleles was not associated with higher parasitism in either sexual diploids or gynogens. Conclusions The differences in MHC diversity between gynogenetic triploids and sexual diploids are in accordance with the hypothesis of sexually-mediated selection increasing MHC diversity and fulfil a prerequisite of the Red Queen hypothesis. The different patterns in PPS between gynogens and sexual gibel carp also suggest the potential role of sexual selection and supports parasite-mediated selection maintaining MHC diversity. We showed that the most common MHC genotypes of gynogenetic triploids are the target of parasite selection. Our results suggest that the MHC genotype in gibel carp is more important than allelic number for immunocompetence.
ER  -

VETEŠNÍKOVÁ ŠIMKOVÁ, Andrea, Martin KOŠAŘ, Lukáš VETEŠNÍK a Martina MRKVICOVÁ. MHC genes and parasitism in Carassius gibelio, a diploid-triploid fish species with dual reproduction strategies. \textit{BMC Evolutionary Biology}. BioMed Central, 2013, roč.~13, JUN 14 2013, s.~122-136. ISSN~1471-2148. Dostupné z: https://dx.doi.org/10.1186/1471-2148-13-122.

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