KREJČÍ, Jan, Pavel GREGOR, David ZEMANEK, Klaudia VYSKOČILOVÁ, Karol CURILA, Radka STEPANOVA, Miroslav NOVÁK, Ladislav GROCH and Josef VESELKA. Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy. The Scientific World Journal. NY, USA: HINDAWI PUBLISHING CORPORATION, 2013, vol. 2013, "neuvedeno", p. 629650-629656. ISSN 1537-744X. Available from: https://dx.doi.org/10.1155/2013/629650.
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Basic information
Original name Comparison of Long-Term Effect of Dual-Chamber Pacing and Alcohol Septal Ablation in Patients with Hypertrophic Obstructive Cardiomyopathy
Authors KREJČÍ, Jan (203 Czech Republic, guarantor, belonging to the institution), Pavel GREGOR (203 Czech Republic), David ZEMANEK (203 Czech Republic), Klaudia VYSKOČILOVÁ (703 Slovakia, belonging to the institution), Karol CURILA (203 Czech Republic), Radka STEPANOVA (203 Czech Republic), Miroslav NOVÁK (203 Czech Republic, belonging to the institution), Ladislav GROCH (203 Czech Republic, belonging to the institution) and Josef VESELKA (203 Czech Republic).
Edition The Scientific World Journal, NY, USA, HINDAWI PUBLISHING CORPORATION, 2013, 1537-744X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.219
RIV identification code RIV/00216224:14110/13:00072509
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1155/2013/629650
UT WoS 000327333400001
Keywords in English OUTFLOW TRACT OBSTRUCTION; LEFT-VENTRICULAR HYPERTROPHY; FOLLOW-UP; PACEMAKER IMPLANTATION; SUBAORTIC STENOSIS; DOUBLE-BLIND; REDUCTION; CROSSOVER; BENEFITS; THERAPY
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 5/3/2014 09:42.
Abstract
Introduction. Nonpharmacological treatment of patients with hypertrophic obstructive cardiomyopathy (HOCM) comprises surgical myectomy (SME), alcohol septal ablation (ASA), and dual-chamber (DDD) pacing. The aim of the study was to compare the long-term effect of DDD pacing and ASA in symptomatic HOCM patients. Patients and Methods. We evaluated retrospective data from three cardiocenters; there were 24 patients treated with DDD pacing included and 52 treated with ASA followed for 101 +/- 49 and 87 +/- 23 months, respectively. Results. In the group treated with DDD pacing, the left ventricle outflow tract gradient (LVOTG) decreased from 82 +/- 44mmHg to 21 +/- 21mmHg, and NYHA class improved from 2.7 +/- 0.5 to 2.1 +/- 0.6 (both P < 0.001). In the ASA-treated group, a decline in LVOTG from 73 +/- 38mmHg to 24 +/- 26 mmHg and reduction in NYHA class from 2.8 +/- 0.5 to 1.7 +/- 0.8 were observed (both P < 0.001). The LVOTG change was similar in both groups (P = 0.264), and symptoms were more affected by ASA (P = 0.001). Conclusion. ASA and DDD pacing were similarly effective in reducing LVOTG. The symptoms improvement was more expressed in patients treated with ASA.
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