C 2014

Tissue visualization mediated by nanoparticles: from tissue staining to mass spectrometry tissue profiling and imaging

KOLÁŘOVÁ, Lenka, Petr VAŇHARA, Eladia Maria PEŇA MENDÉZ, Aleš HAMPL, Josef HAVEL et. al.

Basic information

Original name

Tissue visualization mediated by nanoparticles: from tissue staining to mass spectrometry tissue profiling and imaging

Authors

KOLÁŘOVÁ, Lenka (203 Czech Republic, belonging to the institution), Petr VAŇHARA (203 Czech Republic, belonging to the institution), Eladia Maria PEŇA MENDÉZ (724 Spain), Aleš HAMPL (203 Czech Republic, belonging to the institution) and Josef HAVEL (203 Czech Republic, guarantor, belonging to the institution)

Edition

1st. Manchester (UK), Nanomedicine, p. 467-488, 22 pp. 2014

Publisher

One Central Press (OCP)

Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

10406 Analytical chemistry

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

RIV identification code

RIV/00216224:14310/14:00073532

Organization unit

Faculty of Science

ISBN

978-1-910086-01-8

Keywords in English

Histology; Staining; Tissue imaging; Mass spectrometry; Nanomedicine; Nanoparticles

Tags

Změněno: 27/4/2015 16:59, Mgr. Lenka Kolářová, Ph.D.

Abstract

V originále

An extensive progress in nanotechnology led to development of variety of nanoparticles capable of specific interactions with biological structures even in living organisms. Structure and chemical properties of nanoparticles can be tailored to fit desired tasks, ranging from drug delivery to cell tracking or histopathological studies. Classical histological staining techniques of tissue sections can be complemented by information brought by specific deposition of nanoparticles in tissues and their direct visualization. Moreover, nanoparticles can enhance outputs of bioanalytical techniques, such as mass spectrometry, providing an insight to the tissue composition in a topological context. Nanoparticles applied in tissue visualization therefore contribute to composing of a complex image that broadens frontiers of current diagnostics and tissue-oriented research.

Links

ED2.1.00/03.0086, research and development project
Name: Regionální VaV centrum pro nízkonákladové plazmové a nanotechnologické povrchové úpravy
GA202/07/1669, research and development project
Name: Depozice termomechanicky stabilních nanostrukturovaných diamantu-podobných tenkých vrstev ve dvojfrekvenčních kapacitních výbojích
Investor: Czech Science Foundation, Deposition of thermomehanically stable nanostructured diamond-like thin films in dual frequency capacitive discharges
MSM0021622411, plan (intention)
Name: Studium a aplikace plazmochemických reakcí v neizotermickém nízkoteplotním plazmatu a jeho interakcí s povrchem pevných látek
Investor: Ministry of Education, Youth and Sports of the CR, Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface
MSM0021622430, plan (intention)
Name: Funkční a molekulární charakteristiky nádorových a normálních kmenových buněk - identifikace cílů pro nová terapeutika a terapeutické strategie
Investor: Ministry of Education, Youth and Sports of the CR, Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
MUNI/M/0041/2013, interní kód MU
Name: Bioanalytical Cell and Tissue Authentication using Physical Chemistry Methods and Artificial Intelligence
Investor: Masaryk University, INTERDISCIPLINARY - Interdisciplinary research projects