| KRAUS, Jaroslav, Eva NÁRTOVÁ, Emil PAVLÍK, Rami KATRA, Ivan ŠTERZL a Jaromír ASTL. Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children. ACTA OTO-LARYNGOLOGICA. LONDON: INFORMA HEALTHCARE, 2014, roč. 134, č. 1, s. 88-92. ISSN 0001-6489. Dostupné z: https://dx.doi.org/10.3109/00016489.2013.840924. |
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@article{1170231,
author = {Kraus, Jaroslav and Nártová, Eva and Pavlík, Emil and Katra, Rami and Šterzl, Ivan and Astl, Jaromír},
article_location = {LONDON},
article_number = {1},
doi = {http://dx.doi.org/10.3109/00016489.2013.840924},
keywords = {Adenoid; tonsils; PCR; pharynx},
language = {eng},
issn = {0001-6489},
journal = {ACTA OTO-LARYNGOLOGICA},
title = {Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children},
volume = {134},
year = {2014}
}
TY - JOUR
ID - 1170231
AU - Kraus, Jaroslav - Nártová, Eva - Pavlík, Emil - Katra, Rami - Šterzl, Ivan - Astl, Jaromír
PY - 2014
TI - Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children
JF - ACTA OTO-LARYNGOLOGICA
VL - 134
IS - 1
SP - 88-92
EP - 88-92
PB - INFORMA HEALTHCARE
SN - 00016489
KW - Adenoid
KW - tonsils
KW - PCR
KW - pharynx
N2 - Conclusion: Our results encourage the notion that the pharynx could be an extragastric reservoir of Helicobacter pylori (HP). The study confirmed the presence of HP in adenotonsillar tissue in children. It could have importance in the pathophysiology of upper respiratory diseases. However, its precise role in these processes remains unclear and requires further studies. Objective: A prospective study was carried out to evaluate the presence of HP in tonsillar and adenoid tissue in children. The study focused on real-time PCR analyzing CagA and VacA genotypes of HP strains. Methods: A total of 37 consecutive pediatric patients with adenotonsillar hypertrophy indicated for surgery were observed in a prospective study. Adenoidectomy and/or tonsillectomy was performed in each patient; 49 specimens were taken, 32 from adenoids and 17 from tonsils. The presence of HP and its genotype were tested in all samples by real-time PCR analysis. Results: Of 49 samples analyzed, 48 were positive for the presence of HP (98%), so only 1 sample was negative. While the genotype VacAs1bm2 was definitely dominant in adenoid tissue, wider distribution was observed in tonsillar tissue. Cag(+) strains represented one-fifth of all samples (21%).
ER -
KRAUS, Jaroslav, Eva NÁRTOVÁ, Emil PAVLÍK, Rami KATRA, Ivan ŠTERZL a Jaromír ASTL. Prevalence of Helicobacter pylori in adenotonsillar hypertrophy in children. \textit{ACTA OTO-LARYNGOLOGICA}. LONDON: INFORMA HEALTHCARE, 2014, roč.~134, č.~1, s.~88-92. ISSN~0001-6489. Dostupné z: https://dx.doi.org/10.3109/00016489.2013.840924.
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