Influence of cerebellar stereotactic stimulation on left-right
electrodermal information transference in a patient with
cerebral palsy

J 2013

Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy

BOB, Petr, Tomas GALANDA, Peter JOMBÍK, Jiří RABOCH, Miroslav GALANDA et. al.

Základní údaje

Originální název

Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy

Autoři

BOB, Petr (203 Česká republika, garant, domácí), Tomas GALANDA (703 Slovensko), Peter JOMBÍK (703 Slovensko), Jiří RABOCH (203 Česká republika) a Miroslav GALANDA (703 Slovensko)

Vydání

Neuropsychiatric Disease and Treatment, Aukland, Dove Medical Press, 2013, 1176-6328

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Nový Zéland

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.154

Kód RIV

RIV/00216224:14740/13:00072795

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.2147/NDT.S52947

UT WoS

000327739700001

Klíčová slova anglicky

autonomic laterality; bilateral electrodermal activity; cerebral palsy; epileptiform activity; interhemispheric interaction; stereotactic cerebellar stimulation

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 30. 3. 2014 21:52, Olga Křížová

Anotace

V originále

Background and objectives: Recent evidence indicates that cerebral palsy is connected to specific autonomic dysregulation between sympathetic and parasympathetic efferent pathways, likely linked to hemispheric influences. These findings suggest a hypothesis that contralateral interhemispheric disinhibition, which may occur on various levels of brain processing including motor functions, could be linked to specific functional dysregulation and structural lesions, which may play a specific role in the modulation of autonomic functions and lead to autonomic dysregulation in cerebral palsy. Method: With the aim of comparing autonomic functions as they relate to interhemispheric modulatory influences during therapeutically indicated stereotactic cerebellar stimulation, we have performed bilateral electrodermal activity measurement and calculations of pointwise transinformation (PTI) in a patient with cerebral palsy. Measurement was performed during therapeutic deep cerebellar stimulation in two cerebellar areas in anterior cerebellar lobe-culmen (left electrode) and central lobule-superior cerebellar peduncle (right electrode). Results: The results indicate that information transference (PTI) is able to distinguish the states related to specific cerebellar stimulations and that lowest levels of the PTI have been found during stimulation of the central lobule-superior cerebellar peduncle (electrode deepest contact 1), indicating a significantly increased level of inhibition between the left and right sides. Conclusion: The results may present potentially useful clinical findings indicating that increased PTI calculated from electrodermal activity could indirectly indicate disinhibitory activity as a possible indicator of a failure of interhemispheric communication that could explain some specific pathogenetic mechanisms in cerebral palsy. Nevertheless, these results need detailed confirmation in further research, as well as reliable clinical evaluation of their usefulness in the therapy of cerebral palsy.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

BOB, Petr, Tomas GALANDA, Peter JOMBÍK, Jiří RABOCH a Miroslav GALANDA. Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy. Neuropsychiatric Disease and Treatment. Aukland: Dove Medical Press, 2013, roč. 9, Nov, s. 1853-1857. ISSN 1176-6328. Dostupné z: https://dx.doi.org/10.2147/NDT.S52947.

@article{1173746,
   author = {Bob, Petr and Galanda, Tomas and Jombík, Peter and Raboch, Jiří and Galanda, Miroslav},
   article_location = {Aukland},
   article_number = {Nov},
   doi = {http://dx.doi.org/10.2147/NDT.S52947},
   keywords = {autonomic laterality; bilateral electrodermal activity; cerebral palsy; epileptiform activity; interhemispheric interaction; stereotactic cerebellar stimulation},
   language = {eng},
   issn = {1176-6328},
   journal = {Neuropsychiatric Disease and Treatment},
   title = {Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy},
   url = {http://www.dovepress.com/influence-of-cerebellar-stereotactic-stimulation-on-leftndashright-ele-peer-reviewed-article-NDT},
   volume = {9},
   year = {2013}
}

TY  - JOUR
ID  - 1173746
AU  - Bob, Petr - Galanda, Tomas - Jombík, Peter - Raboch, Jiří - Galanda, Miroslav
PY  - 2013
TI  - Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy
JF  - Neuropsychiatric Disease and Treatment
VL  - 9
IS  - Nov
SP  - 1853-1857
EP  - 1853-1857
PB  - Dove Medical Press
SN  - 11766328
KW  - autonomic laterality
KW  - bilateral electrodermal activity
KW  - cerebral palsy
KW  - epileptiform activity
KW  - interhemispheric interaction
KW  - stereotactic cerebellar stimulation
UR  - http://www.dovepress.com/influence-of-cerebellar-stereotactic-stimulation-on-leftndashright-ele-peer-reviewed-article-NDT
L2  - http://www.dovepress.com/influence-of-cerebellar-stereotactic-stimulation-on-leftndashright-ele-peer-reviewed-article-NDT
N2  - Background and objectives: Recent evidence indicates that cerebral palsy is connected to specific autonomic dysregulation between sympathetic and parasympathetic efferent pathways, likely linked to hemispheric influences. These findings suggest a hypothesis that contralateral interhemispheric disinhibition, which may occur on various levels of brain processing including motor functions, could be linked to specific functional dysregulation and structural lesions, which may play a specific role in the modulation of autonomic functions and lead to autonomic dysregulation in cerebral palsy. Method: With the aim of comparing autonomic functions as they relate to interhemispheric modulatory influences during therapeutically indicated stereotactic cerebellar stimulation, we have performed bilateral electrodermal activity measurement and calculations of pointwise transinformation (PTI) in a patient with cerebral palsy. Measurement was performed during therapeutic deep cerebellar stimulation in two cerebellar areas in anterior cerebellar lobe-culmen (left electrode) and central lobule-superior cerebellar peduncle (right electrode). Results: The results indicate that information transference (PTI) is able to distinguish the states related to specific cerebellar stimulations and that lowest levels of the PTI have been found during stimulation of the central lobule-superior cerebellar peduncle (electrode deepest contact 1), indicating a significantly increased level of inhibition between the left and right sides. Conclusion: The results may present potentially useful clinical findings indicating that increased PTI calculated from electrodermal activity could indirectly indicate disinhibitory activity as a possible indicator of a failure of interhemispheric communication that could explain some specific pathogenetic mechanisms in cerebral palsy. Nevertheless, these results need detailed confirmation in further research, as well as reliable clinical evaluation of their usefulness in the therapy of cerebral palsy.
ER  -

BOB, Petr, Tomas GALANDA, Peter JOMBÍK, Jiří RABOCH a Miroslav GALANDA. Influence of cerebellar stereotactic stimulation on left-right electrodermal information transference in a patient with cerebral palsy. \textit{Neuropsychiatric Disease and Treatment}. Aukland: Dove Medical Press, 2013, roč.~9, Nov, s.~1853-1857. ISSN~1176-6328. Dostupné z: https://dx.doi.org/10.2147/NDT.S52947.

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