Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein
in Sciatica Patients

J 2013

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

UHER, Tomas a Petr BOB

Základní údaje

Originální název

Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients

Autoři

UHER, Tomas (203 Česká republika) a Petr BOB (203 Česká republika, garant, domácí)

Vydání

International Journal of Neuroscience, London, Informa Healthcare, 2013, 0020-7454

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 1.528

Kód RIV

RIV/00216224:14740/13:00072798

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.3109/00207454.2012.746335

UT WoS

000314898000009

Klíčová slova anglicky

C-reactive protein; depressive symptoms; neuropathic pain; sciatica pain

Štítky

ok, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 30. 3. 2014 22:14, Olga Křížová

Anotace

V originále

There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

Citovat

UHER, Tomas a Petr BOB. Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients. International Journal of Neuroscience. London: Informa Healthcare, 2013, roč. 123, č. 3, s. 204-208. ISSN 0020-7454. Dostupné z: https://dx.doi.org/10.3109/00207454.2012.746335.

@article{1173750,
   author = {Uher, Tomas and Bob, Petr},
   article_location = {London},
   article_number = {3},
   doi = {http://dx.doi.org/10.3109/00207454.2012.746335},
   keywords = {C-reactive protein; depressive symptoms; neuropathic pain; sciatica pain},
   language = {eng},
   issn = {0020-7454},
   journal = {International Journal of Neuroscience},
   title = {Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients},
   volume = {123},
   year = {2013}
}

TY  - JOUR
ID  - 1173750
AU  - Uher, Tomas - Bob, Petr
PY  - 2013
TI  - Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients
JF  - International Journal of Neuroscience
VL  - 123
IS  - 3
SP  - 204-208
EP  - 204-208
PB  - Informa Healthcare
SN  - 00207454
KW  - C-reactive protein
KW  - depressive symptoms
KW  - neuropathic pain
KW  - sciatica pain
N2  - There is evidence that neuropathic pain component in low back pain (LBP) patients is associated with higher ratings of comorbidities such as depression and anxiety disorders. In line with current findings, the purpose of this clinical study is to examine a hypothesis regarding a relationship of neuropathic pain component, depression, and other psychopathological symptoms in a specific group of LBP patients with sciatica pain. With respect to findings that depression is related to inflammatory changes, and inflammatory mediators may play a role in neuropathic pain generation, we have assessed also serum C-reactive protein (CRP). Results of the present study show that increased neuropathic pain component in sciatica patients is associated with elevated levels of depression, anxiety, alexithymia, and serum CRP levels. In conclusion, results of this study indicate that CRP levels in sciatica patients are closely associated with neuropathic pain.
ER  -

UHER, Tomas a Petr BOB. Neuropathic Pain, Depressive Symptoms, and C-Reactive Protein in Sciatica Patients. \textit{International Journal of Neuroscience}. London: Informa Healthcare, 2013, roč.~123, č.~3, s.~204-208. ISSN~0020-7454. Dostupné z: https://dx.doi.org/10.3109/00207454.2012.746335.

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