2014
Behavioral Rodent Models of Eating Disorders
KUČEROVÁ, Jana; Zuzana BABINSKÁ a Liana FATTOREZákladní údaje
Originální název
Behavioral Rodent Models of Eating Disorders
Název česky
Behaviorální hlodavčí modely poruch příjmu potravy
Autoři
KUČEROVÁ, Jana (203 Česká republika, garant, domácí); Zuzana BABINSKÁ (703 Slovensko, domácí) a Liana FATTORE (380 Itálie)
Vydání
New York, Appetite, od s. 71-96, 26 s. Human Anatomy and Physiology, 2014
Nakladatel
Nova Science Publishers
Další údaje
Jazyk
angličtina
Typ výsledku
Kapitola resp. kapitoly v odborné knize
Obor
30104 Pharmacology and pharmacy
Stát vydavatele
Spojené státy
Utajení
není předmětem státního či obchodního tajemství
Forma vydání
elektronická verze "online"
Kód RIV
RIV/00216224:14110/14:00075510
Organizační jednotka
Lékařská fakulta
ISBN
978-1-63117-243-4
Klíčová slova česky
anorexia nervosa; bulimia nervosa; binging; zvířecí model
Klíčová slova anglicky
anorexia nervosa; bulimia nervosa; binging; animal model
Štítky
Příznaky
Mezinárodní význam
Změněno: 8. 1. 2015 15:33, Soňa Böhmová
Anotace
V originále
Eating disorders represent an unmet medical need which implies a serious burden for the patients and their families. While anorexia nervosa and bulimia nervosa are among the most widely reported diseases, the newly published DSM-5 has recently distinguished the – thus far – diagnostically neglected binge-eating disorder as a specific nosologic unit for the first time. Available therapeutic options for the treatment of eating disorders are very limited and generally based on psychological or psychiatric interventions. However, pharmacological research exploiting numerous physiological signaling systems is currently being conducted in order to develop innovative therapies of these disorders. This research calls for a wide range of animal models which must be wisely employed with respect for the purpose of individual studies and the validity of particular models. The objective of this chapter is to provide an overview of well-validated behavioral animal models of anorexia nervosa, bulimia nervosa, binge eating and operant conditioning for natural rewards with special attention dedicated to evidence of face, construct and predictive validities of these models and potential sex-dependent differences.