HANÁKOVÁ, Petra, Milan BRÁZDIL, Zdeněk NOVÁK, Jan HEMZA, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Markéta HERMANOVÁ, Marta PAŽOURKOVÁ, Ivan REKTOR a Robert KUBA. Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy. Seizure. Elsevier, 2014, roč. 23, č. 4, s. 266-273. ISSN 1059-1311. Dostupné z: https://dx.doi.org/10.1016/j.seizure.2013.12.003. |
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@article{1186438, author = {Hanáková, Petra and Brázdil, Milan and Novák, Zdeněk and Hemza, Jan and Chrastina, Jan and Ošlejšková, Hana and Hermanová, Markéta and Pažourková, Marta and Rektor, Ivan and Kuba, Robert}, article_number = {4}, doi = {http://dx.doi.org/10.1016/j.seizure.2013.12.003}, keywords = {Epilepsy surgery; Extratemporal; Long-term outcome; Histopathology; Engel's classification}, language = {eng}, issn = {1059-1311}, journal = {Seizure}, title = {Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy}, volume = {23}, year = {2014} }
TY - JOUR ID - 1186438 AU - Hanáková, Petra - Brázdil, Milan - Novák, Zdeněk - Hemza, Jan - Chrastina, Jan - Ošlejšková, Hana - Hermanová, Markéta - Pažourková, Marta - Rektor, Ivan - Kuba, Robert PY - 2014 TI - Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy JF - Seizure VL - 23 IS - 4 SP - 266-273 EP - 266-273 PB - Elsevier SN - 10591311 KW - Epilepsy surgery KW - Extratemporal KW - Long-term outcome KW - Histopathology KW - Engel's classification N2 - Purpose: We analyzed the long-term postoperative outcome and possible predictive factors of the outcome in surgically treated patients with refractory extratemporal epilepsy. Methods: We retrospectively analyzed 73 patients who had undergone resective surgery at the Epilepsy Center Brno between 1995 and 2010 and who had reached at least 1 year outcome after the surgery. The average age at surgery was 28.3 +/- 11.4 years. Magnetic resonance imaging (MRI) did not reveal any lesion in 24 patients (32.9%). Surgical outcome was assessed annually using Engel's modified classification until 5 years after surgery and at the latest follow-up visit. Results: Following the surgery, Engel Class I outcome was found in 52.1% of patients after 1 year, in 55.0% after 5 years, and in 50.7% at the last follow-up visit (average 6.15 +/- 3.84 years). Of the patients who reached the 5-year follow-up visit (average of the last follow-up 9.23 years), 37.5% were classified as Engel IA at each follow-up visit. Tumorous etiology and lesions seen in preoperative MRI were associated with significantly better outcome (p = 0.035; p < 0.01). Postoperatively, 9.6% patients had permanent neurological deficits. Conclusion: Surgical treatment of refractory extratemporal epilepsy is an effective procedure. The presence of a visible MRI-detected lesion and tumorous etiology is associated with significantly better outcome than the absence of MRI-detected lesion or other etiology. ER -
HANÁKOVÁ, Petra, Milan BRÁZDIL, Zdeněk NOVÁK, Jan HEMZA, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Markéta HERMANOVÁ, Marta PAŽOURKOVÁ, Ivan REKTOR a Robert KUBA. Long-term outcome and predictors of resective surgery prognosis in patients with refractory extratemporal epilepsy. \textit{Seizure}. Elsevier, 2014, roč.~23, č.~4, s.~266-273. ISSN~1059-1311. Dostupné z: https://dx.doi.org/10.1016/j.seizure.2013.12.003.
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