J 2014

Symmetry of the Fornix Using Diffusion Tensor Imaging

SBOTO-FRANKENSTEIN, Uta N., Tiffany LAZAR, Bruce R. BOLSTER, Sunny THIND, Patricia Dreessen DE GERVAI et. al.

Základní údaje

Originální název

Symmetry of the Fornix Using Diffusion Tensor Imaging

Autoři

SBOTO-FRANKENSTEIN, Uta N. (124 Kanada), Tiffany LAZAR (124 Kanada), Bruce R. BOLSTER (124 Kanada), Sunny THIND (124 Kanada), Patricia Dreessen DE GERVAI (124 Kanada), Marco L.H. GRUWEL (124 Kanada), Stephen D. SMITH (124 Kanada) a Boguslaw TOMANEK (616 Polsko, garant, domácí)

Vydání

Journal of Magnetic Resonance Imaging, Hoboken (USA), Wiley- Blackwell, 2014, 1053-1807

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 3.210

Kód RIV

RIV/00216224:14740/14:00075878

Organizační jednotka

Středoevropský technologický institut

DOI

UT WoS

000342342500022

Klíčová slova anglicky

Asymmetry; Diffusion tensor imaging; Fornix; TBSS; Tractography

Štítky

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 5. 12. 2014 08:48, Martina Prášilová

Anotace

V originále

Purpose: To: 1) Present fornix tractography in its entirety for 20 healthy individuals to assess variability. 2) Provide individual and groupwise whole tract diffusion parameter symmetry assessments prior to clinical application. 3) Compare whole tract diffusion parameter assessments with tract-based spatial statistics (TBSS). Materials and Methods: Diffusion tensor imaging (DTI) data were acquired on a 3T Siemens magnetic resonance imaging (MRI) system using a single-shot spin echo planar imaging (EPI) sequence. Individual fornix tractography was conducted and whole tract diffusion parameter symmetries assessed. Whole tract results were compared with asymmetry contrasts conducted with voxelwise statistical analysis of diffusion parameters using TBSS. Results: The fornix tract could be visualized in its entirety including the columns, body, crura, and fimbria. Contrary to the crus and body, there were some tractography inconsistencies of the columns and fimbria across subjects. Although whole tract diffusion parameter asymmetries were nonsignificant, fractional anisotropy (FA) values bordered on statistical significance (P = 0.052). Using TBSS, significant FA asymmetries were identified (P less than or equal 0.01, corrected). Conclusion: The findings demonstrate consistency of fornix tractography as well as some variability in the columns and fimbria. While parametric assessment demonstrates diffusion parameter symmetry, permutation-based TBSS analysis reveals significant FA asymmetries in the crura and fimbriae. © 2013 Wiley Periodicals, Inc.