Subthalamic nucleus involvement in executive functions with
increased cognitive load: a subthalamic nucleus and anterior
cingulate cortex depth recording study

J 2014

Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study

AULICKÁ, Štefánia, Pavel JURÁK, Jan CHLÁDEK, Pavel DANIEL, Josef HALÁMEK et. al.

Základní údaje

Originální název

Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study

Autoři

AULICKÁ, Štefánia (703 Slovensko, domácí), Pavel JURÁK (203 Česká republika), Jan CHLÁDEK (203 Česká republika), Pavel DANIEL (203 Česká republika, domácí), Josef HALÁMEK (203 Česká republika), Marek BALÁŽ (703 Slovensko, domácí), Martina BOČKOVÁ (203 Česká republika, domácí), Jan CHRASTINA (203 Česká republika, domácí) a Ivan REKTOR (203 Česká republika, garant, domácí)

Vydání

Journal of Neural Transmission, Wien, SPRINGER WIEN, 2014, 0300-9564

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Rakousko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 2.402

Kód RIV

RIV/00216224:14740/14:00073741

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1007/s00702-014-1191-5

UT WoS

000342453500009

Klíčová slova anglicky

ERD/S; Anterior cingulate cortex; Subthalamic nucleus; Flanker test; Executive functions

Štítky

EL OK, kontrola MP, MP, podil, rivok, SCOPUS

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 26. 1. 2015 10:23, Martina Prášilová

Anotace

V originále

We studied the appearance of broadband oscillatory changes (ranging 2–45 Hz) induced by a cognitive task with two levels of complexity. The event-related de/synchronizations (ERD/S) in the subthalamic nucleus (STN) and in the anterior cingulate cortex (ACC) were evaluated in an executive function test. Four epilepsy surgery candidates with intracerebral electrodes implanted in the ACC and three Parkinson’s disease patients with externalized deep brain stimulation electrodes implanted in the STN participated in the study. A Flanker test (FT) with visual stimuli (arrows) was performed. Subjects reacted to four types of stimuli presented on the monitor by pushing the right or left button: congruent arrows to the right or left side (simple task) and incongruent arrows to the right or left side (more difficult complex task). We explored the activation of STN and the activation of the ACC while processing the FT. Both conditions, i.e. congruent and incongruent, induced oscillatory changes in the ACC and also STN with significantly higher activation during incongruent trial. At variance with the ACC, in the STN not only the ERD beta but also the ERD alpha activity was significantly more activated by the incongruent condition. In line with our earlier studies, the STN appears to be involved in activities linked with increased cognitive load. The specificity and complexity of task-related activation of the STN might indicate the involvement of the STN in processes controlling human behaviour, e.g. in the selection and inhibition of competing alternatives.

Návaznosti

ED1.1.00/02.0068, projekt VaV

Název: CEITEC - central european institute of technology

GAP103/11/0933, projekt VaV

Název: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Investor: Grantová agentura ČR, Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod

Přiložené soubory

ZVV_2014_021_1192652_Subthalamic_nucleus.pdf

Požádat o autorskou verzi souboru

Citovat

AULICKÁ, Štefánia, Pavel JURÁK, Jan CHLÁDEK, Pavel DANIEL, Josef HALÁMEK, Marek BALÁŽ, Martina BOČKOVÁ, Jan CHRASTINA a Ivan REKTOR. Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study. Journal of Neural Transmission. Wien: SPRINGER WIEN, 2014, roč. 121, č. 10, s. 1287-1296. ISSN 0300-9564. Dostupné z: https://dx.doi.org/10.1007/s00702-014-1191-5.

@article{1192652,
   author = {Aulická, Štefánia and Jurák, Pavel and Chládek, Jan and Daniel, Pavel and Halámek, Josef and Baláž, Marek and Bočková, Martina and Chrastina, Jan and Rektor, Ivan},
   article_location = {Wien},
   article_number = {10},
   doi = {http://dx.doi.org/10.1007/s00702-014-1191-5},
   keywords = {ERD/S; Anterior cingulate cortex; Subthalamic nucleus; Flanker test; Executive functions},
   language = {eng},
   issn = {0300-9564},
   journal = {Journal of Neural Transmission},
   title = {Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study},
   url = {http://link.springer.com/article/10.1007%2Fs00702-014-1191-5},
   volume = {121},
   year = {2014}
}

TY  - JOUR
ID  - 1192652
AU  - Aulická, Štefánia - Jurák, Pavel - Chládek, Jan - Daniel, Pavel - Halámek, Josef - Baláž, Marek - Bočková, Martina - Chrastina, Jan - Rektor, Ivan
PY  - 2014
TI  - Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study
JF  - Journal of Neural Transmission
VL  - 121
IS  - 10
SP  - 1287-1296
EP  - 1287-1296
PB  - SPRINGER WIEN
SN  - 03009564
KW  - ERD/S
KW  - Anterior cingulate cortex
KW  - Subthalamic nucleus
KW  - Flanker test
KW  - Executive functions
UR  - http://link.springer.com/article/10.1007%2Fs00702-014-1191-5
L2  - http://link.springer.com/article/10.1007%2Fs00702-014-1191-5
N2  - We studied the appearance of broadband oscillatory changes (ranging 2–45 Hz) induced by a cognitive task with two levels of complexity. The event-related de/synchronizations (ERD/S) in the subthalamic nucleus (STN) and in the anterior cingulate cortex (ACC) were evaluated in an executive function test. Four epilepsy surgery candidates with intracerebral electrodes implanted in the ACC and three Parkinson’s disease patients with externalized deep brain stimulation electrodes implanted in the STN participated in the study. A Flanker test (FT) with visual stimuli (arrows) was performed. Subjects reacted to four types of stimuli presented on the monitor by pushing the right or left button: congruent arrows to the right or left side (simple task) and incongruent arrows to the right or left side (more difficult complex task). We explored the activation of STN and the activation of the ACC while processing the FT. Both conditions, i.e. congruent and incongruent, induced oscillatory changes in the ACC and also STN with significantly higher activation during incongruent trial. At variance with the ACC, in the STN not only the ERD beta but also the ERD alpha activity was significantly more activated by the incongruent condition. In line with our earlier studies, the STN appears to be involved in activities linked with increased cognitive load. The specificity and complexity of task-related activation of the STN might indicate the involvement of the STN in processes controlling human behaviour, e.g. in the selection and inhibition of competing alternatives.
ER  -

AULICKÁ, Štefánia, Pavel JURÁK, Jan CHLÁDEK, Pavel DANIEL, Josef HALÁMEK, Marek BALÁŽ, Martina BOČKOVÁ, Jan CHRASTINA a Ivan REKTOR. Subthalamic nucleus involvement in executive functions with increased cognitive load: a subthalamic nucleus and anterior cingulate cortex depth recording study. \textit{Journal of Neural Transmission}. Wien: SPRINGER WIEN, 2014, roč.~121, č.~10, s.~1287-1296. ISSN~0300-9564. Dostupné z: https://dx.doi.org/10.1007/s00702-014-1191-5.

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