VARGA, Marian, Monika ZOUHAROVÁ, Roman PANTŮČEK, Marek MOŠA a Jiří DOŠKAŘ. Analyzing the defense strategies of Staphylococcus aureus strains against polyvalent bacteriophages. In International Symposium on Staphylococci & Staphylococcal Infections - ISSSI 2014, Chicago, IL, USA. 2014. |
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@proceedings{1196734, author = {Varga, Marian and Zouharová, Monika and Pantůček, Roman and Moša, Marek and Doškař, Jiří}, booktitle = {International Symposium on Staphylococci & Staphylococcal Infections - ISSSI 2014, Chicago, IL, USA}, language = {eng}, title = {Analyzing the defense strategies of Staphylococcus aureus strains against polyvalent bacteriophages}, url = {http://isssi2014.com/}, year = {2014} }
TY - CONF ID - 1196734 AU - Varga, Marian - Zouharová, Monika - Pantůček, Roman - Moša, Marek - Doškař, Jiří PY - 2014 TI - Analyzing the defense strategies of Staphylococcus aureus strains against polyvalent bacteriophages UR - http://isssi2014.com/ N2 - The emergence and alarming increase of multiresistant strains of Staphylococcus aureus emphasizes the need for new and inovative antimicrobial strategies. One of them is phage therapy that represents a promising alternative to the use of antibiotics for combating bacterial infections. Some strains, however, are resistant to therapeutic bacteriophages, which may decrease the effectivity of phage-based drugs. In our study, we analyzed causes responsible for this resistance, mainly: (i) efficacy of phage adsorption to bacterial cells; (ii) interference with the products of the prophage-borne genes in lysogenic strains; and (iii) effect of CRISPR-Cas elements. ER -
VARGA, Marian, Monika ZOUHAROVÁ, Roman PANTŮČEK, Marek MOŠA a Jiří DOŠKAŘ. Analyzing the defense strategies of Staphylococcus aureus strains against polyvalent bacteriophages. In \textit{International Symposium on Staphylococci \&{} Staphylococcal Infections - ISSSI 2014, Chicago, IL, USA}. 2014.
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