| ZAKHAROV, Sergey, Daniela PELCOVA, Tomas NAVRATIL, Jaromir BELACEK, Ivana KURCOVA, Ondrej KOMZAK, Tomas SALEK, Jiri LATTA, Radovan TUREK, Robert BOCEK, Cyril KUCERA, Jaroslav A. HUBACEK, Zdenka FENCLOVA, Vit PETRIK, Martin CERMAK a Knut Erik HOVDA. Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning. Kidney International. New York: NATURE PUBLISHING GROUP, 2014, roč. 86, č. 1, s. 199-207. ISSN 0085-2538. Dostupné z: https://dx.doi.org/10.1038/ki.2014.60. |
Další formáty:
BibTeX
LaTeX
RIS
@article{1198075,
author = {Zakharov, Sergey and Pelcova, Daniela and Navratil, Tomas and Belacek, Jaromir and Kurcova, Ivana and Komzak, Ondrej and Salek, Tomas and Latta, Jiri and Turek, Radovan and Bocek, Robert and Kucera, Cyril and Hubacek, Jaroslav A. and Fenclova, Zdenka and Petrik, Vit and Cermak, Martin and Hovda, Knut Erik},
article_location = {New York},
article_number = {1},
doi = {http://dx.doi.org/10.1038/ki.2014.60},
keywords = {continuous veno-venous hemodialysis; elimination half-life; formate kinetics; intermittent hemodialysis; methanol kinetics; methanol poisoning},
language = {eng},
issn = {0085-2538},
journal = {Kidney International},
title = {Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning},
url = {http://www.nature.com/ki/index.html},
volume = {86},
year = {2014}
}
TY - JOUR
ID - 1198075
AU - Zakharov, Sergey - Pelcova, Daniela - Navratil, Tomas - Belacek, Jaromir - Kurcova, Ivana - Komzak, Ondrej - Salek, Tomas - Latta, Jiri - Turek, Radovan - Bocek, Robert - Kucera, Cyril - Hubacek, Jaroslav A. - Fenclova, Zdenka - Petrik, Vit - Cermak, Martin - Hovda, Knut Erik
PY - 2014
TI - Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning
JF - Kidney International
VL - 86
IS - 1
SP - 199-207
EP - 199-207
PB - NATURE PUBLISHING GROUP
SN - 00852538
KW - continuous veno-venous hemodialysis
KW - elimination half-life
KW - formate kinetics
KW - intermittent hemodialysis
KW - methanol kinetics
KW - methanol poisoning
UR - http://www.nature.com/ki/index.html
N2 - During an outbreak of methanol poisonings in the Czech Republic in 2012, we were able to study methanol and formate elimination half-lives during intermittent hemodialysis (IHD) and continuous veno-venous hemodialysis/hemodiafiltration (CVVHD/HDF) and the relative impact of dialysate and blood flow rates on elimination. Data were obtained from 11 IHD and 13 CVVHD/HDF patients. Serum methanol and formate concentrations were measured by gas chromatography and an enzymatic method. The groups were relatively comparable, but the CVVHD/HDF group was significantly more acidotic (mean pH 6.9 vs. 7.1 IHD). The mean elimination half-life of methanol was 3.7 and formate 1.6 h with IHD, versus 8.1 and 3.6 h, respectively, with CVVHD/HDF (both significant). The 54% greater reduction in methanol and 56% reduction in formate elimination half-life during IHD resulted from the higher blood and dialysate flow rates. Increased blood and dialysate flow on the CVVHD/HDF also increased elimination significantly. Thus, IHD is superior to CVVHD/HDF for more rapid methanol and formate elimination, and if CVVHD/HDF is the only treatment available then elimination is greater with greater blood and dialysate flow rates.
ER -
ZAKHAROV, Sergey, Daniela PELCOVA, Tomas NAVRATIL, Jaromir BELACEK, Ivana KURCOVA, Ondrej KOMZAK, Tomas SALEK, Jiri LATTA, Radovan TUREK, Robert BOCEK, Cyril KUCERA, Jaroslav A. HUBACEK, Zdenka FENCLOVA, Vit PETRIK, Martin CERMAK a Knut Erik HOVDA. Intermittent hemodialysis is superior to continuous veno-venous hemodialysis/hemodiafiltration to eliminate methanol and formate during treatment for methanol poisoning. \textit{Kidney International}. New York: NATURE PUBLISHING GROUP, 2014, roč.~86, č.~1, s.~199-207. ISSN~0085-2538. Dostupné z: https://dx.doi.org/10.1038/ki.2014.60.
|
