| NEVÍDALOVÁ, Hana, Zdeněk GLATZ a Lenka MICHALCOVÁ. Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis. In František Foret, Jana Křenková, Iveta Drobníková, Andras Guttman, Karel Klepárník. 11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014. Brno: Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika, 2014, s. 340-342. ISBN 978-80-904959-2-0. |
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@inproceedings{1205102,
author = {Nevídalová, Hana and Glatz, Zdeněk and Michalcová, Lenka},
address = {Brno},
booktitle = {11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014.},
editor = {František Foret, Jana Křenková, Iveta Drobníková, Andras Guttman, Karel Klepárník},
keywords = {capillary electrophoresis - frontal analysis; competitive binding; HSA; diklofenak},
howpublished = {tištěná verze "print"},
language = {eng},
location = {Brno},
isbn = {978-80-904959-2-0},
pages = {340-342},
publisher = {Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika},
title = {Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis},
url = {http://www.ce-ce.org},
year = {2014}
}
TY - JOUR
ID - 1205102
AU - Nevídalová, Hana - Glatz, Zdeněk - Michalcová, Lenka
PY - 2014
TI - Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis
PB - Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika
CY - Brno
SN - 9788090495920
KW - capillary electrophoresis - frontal analysis
KW - competitive binding
KW - HSA
KW - diklofenak
UR - http://www.ce-ce.org
N2 - The capillary electrophoresis fontal analysis (CE-FA) was used to study the affinities between diclofenac and tryptophan, and human serum albumin (HSA). Apparent log Kb = (4.4 ± 0.01) L/mol for diclofenac–HSA and log Kb = (3.95 ± 0.004) L/mol for tryptophan–HSA have a good repeatability. The displacement experiment shows the displacement of tryptophan from binding site using diclofenac.
ER -
NEVÍDALOVÁ, Hana, Zdeněk GLATZ a Lenka MICHALCOVÁ. Study of competitive binding between diclofenac and tryptophan on hunam serum albumin using capillary electrophoresis. In František Foret, Jana Křenková, Iveta Drobníková, Andras Guttman, Karel Klepárník. \textit{11 th International Interdisciplinary Meeting on Bioanalysis CECE 2014.}. Brno: Institute of Analytical Chemistry AS CR, v. v. i., Brno, Česká republika, 2014, s.~340-342. ISBN~978-80-904959-2-0.
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