a 2014

Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report

JIRSENSKÁ, Zlatava, Michaela MÁCHALOVÁ a Lukáš HOMOLA

Základní údaje

Originální název

Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report

Autoři

JIRSENSKÁ, Zlatava (203 Česká republika, garant, domácí), Michaela MÁCHALOVÁ (203 Česká republika, domácí) a Lukáš HOMOLA (203 Česká republika, domácí)

Vydání

32nd Annual Meeting of the European Society for Pediatric Infectious Diseases, 2014

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30300 3.3 Health sciences

Stát vydavatele

Irsko

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/14:00077208

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

VACCINATION; LARYNGEAL PAPILLOMATOSIS

Štítky

Změněno: 27. 11. 2014 15:57, Soňa Böhmová

Anotace

V originále

We present a case report of one year old girl with recurrent laryngeal papillomatosis that was successfully treated by vaccination. The childs mother got condyloma acuminata during pregnancy. The disease was transmitted to the girl probably during delivery. At age of 5 months, the child started to present difficulties with breathing due to laryngeal papilomas. The disease required frequent papilectomies (almost every month) to maintain breathing. The papilomavirus type 11 was detected by PCR in the papiloma histology sample. At age of 18 months we started experimental vaccination with Gardasil* (it contains particles similar to HPV 6, 11, 16, 18). Intervals between necessary papilectomies were longer after the second dose of the vaccine. There was no need for further polypectomy after the third dose of the vaccine. At age of 30 months the child has no clinical and laryngoscope signs of laryngeal papillomatosis and the girl regained her voice. This case indicates possible new therapeutical approach to recurrent laryngeal papillomatosis.