MICENKOVÁ, Lenka, Petra ŠIŠKOVÁ, Juraj BOSÁK, Ivana JAMBOROVÁ, Lenka ČERNOHORSKÁ a David ŠMAJS. Characterization of Human Uropathogenic ESBL-Producing Escherichia coli in the Czech Republic: Spread of CTX-M-27-Producing Strains in a University Hospital. Microbial Drug Resistance. New Rochelle: Mary Ann Liebert Inc., 2014, roč. 20, č. 6, s. 610-617. ISSN 1076-6294. Dostupné z: https://dx.doi.org/10.1089/mdr.2014.0013. |
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@article{1209760, author = {Micenková, Lenka and Šišková, Petra and Bosák, Juraj and Jamborová, Ivana and Černohorská, Lenka and Šmajs, David}, article_location = {New Rochelle}, article_number = {6}, doi = {http://dx.doi.org/10.1089/mdr.2014.0013}, keywords = {SPECTRUM BETA-LACTAMASES; CTX-M-TYPE; FIELD GEL-ELECTROPHORESIS; POLYMERASE-CHAIN-REACTION; URINARY-TRACT-INFECTIONS; MOLECULAR EPIDEMIOLOGY; VIRULENCE DETERMINANTS; ANTIBIOTIC-RESISTANCE; KLEBSIELLA-PNEUMONIAE; PHYLOGENETIC GROUP}, language = {eng}, issn = {1076-6294}, journal = {Microbial Drug Resistance}, title = {Characterization of Human Uropathogenic ESBL-Producing Escherichia coli in the Czech Republic: Spread of CTX-M-27-Producing Strains in a University Hospital}, volume = {20}, year = {2014} }
TY - JOUR ID - 1209760 AU - Micenková, Lenka - Šišková, Petra - Bosák, Juraj - Jamborová, Ivana - Černohorská, Lenka - Šmajs, David PY - 2014 TI - Characterization of Human Uropathogenic ESBL-Producing Escherichia coli in the Czech Republic: Spread of CTX-M-27-Producing Strains in a University Hospital JF - Microbial Drug Resistance VL - 20 IS - 6 SP - 610-617 EP - 610-617 PB - Mary Ann Liebert Inc. SN - 10766294 KW - SPECTRUM BETA-LACTAMASES KW - CTX-M-TYPE KW - FIELD GEL-ELECTROPHORESIS KW - POLYMERASE-CHAIN-REACTION KW - URINARY-TRACT-INFECTIONS KW - MOLECULAR EPIDEMIOLOGY KW - VIRULENCE DETERMINANTS KW - ANTIBIOTIC-RESISTANCE KW - KLEBSIELLA-PNEUMONIAE KW - PHYLOGENETIC GROUP N2 - Aims: The purpose of this study was to characterize the extended-spectrum b-lactamase (ESBL)-producing uropathogenic Escherichia coli (UPEC) strains isolated in the South Moravia region of the Czech Republic. Results: Out of 109 ESBL-producing UPEC isolates, the CTX-M-15-producing E. coli O25b-ST131 was detected in 55 (50.5%) and the CTX-M-27-producing E. coli O25b-ST131 in 40 isolates (36.7%). Most isolates were distributed among three pulsed-field gel electrophoresis clusters and were characterized by low variability relative to antibiotic resistance patterns, in E. coli phylogroups and by the prevalence of virulence and bacteriocin determinants. Despite this, 14 groups of identical isolates (comprising a total of 41 isolates) were identified when all tested parameters of E. coli were combined. Conclusions: Since the occurrence of E. coli B2-O25b-ST131 CTX-M-27 was only recently described in Asia, the frequent isolation of this lineage among patients in South Moravia suggests an efficient transfer of this clone from Asian countries. The limited variability of detected parameters of ESBL-producing UPEC strains is consistent with a common origin of the analyzed isolates, in which there is an ongoing process of genetic diversification. ER -
MICENKOVÁ, Lenka, Petra ŠIŠKOVÁ, Juraj BOSÁK, Ivana JAMBOROVÁ, Lenka ČERNOHORSKÁ a David ŠMAJS. Characterization of Human Uropathogenic ESBL-Producing Escherichia coli in the Czech Republic: Spread of CTX-M-27-Producing Strains in a University Hospital. \textit{Microbial Drug Resistance}. New Rochelle: Mary Ann Liebert Inc., 2014, roč.~20, č.~6, s.~610-617. ISSN~1076-6294. Dostupné z: https://dx.doi.org/10.1089/mdr.2014.0013.
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