SKORKOVSKÁ, Karolína, Helmut WILHELM, Holger LÜDTKE, Barbara WILHELM and Anne KURTENBACH. Investigation of summation mechanisms in the pupillomotor system. Graefes Archive for Clinical and Experimental Ophthalmology. New York: Springer, 2014, vol. 252, No 7, p. 1155-1160. ISSN 0721-832X. Available from: https://dx.doi.org/10.1007/s00417-014-2677-4.
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Basic information
Original name Investigation of summation mechanisms in the pupillomotor system
Authors SKORKOVSKÁ, Karolína (203 Czech Republic, guarantor, belonging to the institution), Helmut WILHELM (276 Germany), Holger LÜDTKE (276 Germany), Barbara WILHELM (276 Germany) and Anne KURTENBACH (276 Germany).
Edition Graefes Archive for Clinical and Experimental Ophthalmology, New York, Springer, 2014, 0721-832X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.908
RIV identification code RIV/00216224:14110/14:00078357
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s00417-014-2677-4
UT WoS 000338492500017
Keywords in English Pupil; Receptive field; Pupil perimetry; Campimetry
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 15/1/2015 13:09.
Abstract
To ascertain whether the pupillary response amplitude shows spatial summation of responses with increasing size of retinal stimulation, and to examine the pupillary responses for evidence of surround inhibition, analogous to that found in the receptive fields of the retinal ganglion cells. By means of infrared-video-pupillography, the pupil reaction to stimuli of increasing size (1-15A degrees) was measured in 30 normal subjects. Four different retinal locations (0A degrees, 20A degrees and 40A degrees eccentricity on the upper temporal retina and 20A degrees eccentricity on the lower nasal retina) were examined at four different stimulus luminances (17, 47, 87 and 140 cd/m(2)). When the average log amplitude of the pupil light reaction from the 30 subjects is plotted as a function of the log area of the stimulus, a bi-linear response is observed, which is most pronounced for the two higher luminances. The intersection points of the two linear responses are 2.01A degrees in the fovea, 2.80A degrees at 20A degrees upper temporal retina, 2.85A degrees at 20A degrees lower nasal retina and 4.86A degrees at 40A degrees upper temporal retina. This study suggests that pupillomotor summation areas consist of both summation and inhibitory zones. They show larger diameters than receptive fields of retinal ganglion cells and do not appear to reflect pupillary summation areas of the pretectal olivary nucleus luminance neurons.
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